Author

T.-W. Gilberger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Organism:plant (other)· 2 Assay:cryo-EM· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

E. Pietsch· 3 shared P.-C. Burda· 3 shared C. Söhnchen· 2 shared J. Strauss· 2 shared L. Wilcke· 2 shared A. Alder· 1 shared A. Passecker· 1 shared A. Ramaprasad· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

E. Pietsch

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Disruption of a Plasmodium falciparum patatin-like phospholipase delays male gametocyte exflagellation

E. Pietsch, K. Niedermueller, T.-W. Gilberger, P.-C. Burda

This study identifies a patatin-like phospholipase in Plasmodium falciparum that delays male gametocyte exflagellation when disrupted, suggesting a non-essential but important role in gametogenesis.

bioRxiv · Apr 28, 2023 · PreprintMicrobiology

Form follows function: Variable microtubule architecture in the malaria parasite

J. L. Ferreira, V. Prazak, D. Vasishtan, M. Siggel, F. Hentzschel, E. Pietsch, J. Kosinski, F. Frischknecht, T.-W. Gilberger, K. Grünewald

The paper uses electron cryo-tomography to study microtubule architecture in malaria parasites across their life cycle, revealing structural diversity not seen in other organisms.

bioRxiv · Apr 13, 2022Microbiology

Global analysis of putative phospholipases in the malaria parasite Plasmodium falciparum reveals critical factors for parasite proliferation

P.-C. Burda, A. Ramaprasad, E. Pietsch, S. Bielfeld, C. Söhnchen, L. Wilcke, J. Strauss, D. Schwudke, A. Sait, L. M. Collinson, M. J. Blackman, T.-W. Gilberger

The paper identifies essential phospholipases in Plasmodium falciparum, showing PF3D7_1013500 is critical for parasite maturation and PF3D7_1358000 is vital for mitochondrial function and growth.

bioRxiv · Jun 28, 2021 · PreprintMicrobiology

CRISPR/Cas9-engineered inducible gametocyte producer lines as a novel tool for basic and applied research on Plasmodium falciparum malaria transmission stages

S. D. Boltryk, A. Passecker, A. Alder, M. van de Vegte-Bolmer, R. W. Sauerwein, N. M. B. Brancucci, H.-P. Beck, T.-W. Gilberger, T. S. Voss

This paper develops CRISPR/Cas9-engineered inducible gametocyte producer lines for mass production of P. falciparum gametocytes, achieving 75% sexual commitment and enabling genetic studies of transmission stages.

bioRxiv · Oct 5, 2020 · PreprintMicrobiology

Structure-based identification and functional characterization of an essential lipocalin in the malaria parasite Plasmodium falciparum

P.-C. Burda, T. Crosskey, K. Lauk, A. Zurborg, C. Söhnchen, B. Liffner, L. Wilcke, J. Strauss, C. Jeffries, D. I. Svergun, D. W. Wilson, M. Wilmanns, T.-W. Gilberger

This study identifies and characterizes PfLCN, a lipocalin in Plasmodium falciparum, showing its role in oxidative stress response and parasite survival.

bioRxiv · Feb 13, 2020Cell Biology