Author

J. E. Konkel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. S. MacDonald· 2 shared E. L. Houlder· 2 shared J. E. Allen· 2 shared J. R. Grainger· 2 shared L. Boon· 2 shared R. H. Daw· 2 shared A. Chenery· 1 shared A. D. Adamson· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. S. MacDonald

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation.

P. C. Cook, S. L. Brown, E. L. Houlder, S. Baker, F. R. Svedberg, G. Howell, M. Bertuzzi, L. Boon, J. E. Konkel, J. E. Allen, A. S. MacDonald

The paper identifies Mgl2+ cDC2s as key drivers of type 2, but not type 17, fungal allergic airway inflammation in mice.

bioRxiv · Nov 24, 2023Immunology

CD163 and Tim-4 identify resident intestinal macrophages across sub-tissular regions that are spatially regulated by TGF-β

I. E. Prise, V. Jayaraman, V. Kästele, R. H. Daw, K. Wemyss, H. Bridgeman, S. Tamburrano, P. Strangward, C. Chew, L. Martens, C. L. Scott, M. Guilliams, A. D. Adamson, J. E. Konkel, T. N. Shaw, J. R. Grainger

The paper identifies CD163 and Tim-4 as markers for intestinal macrophages and shows TGF-β regulates their spatial distribution in different niches.

bioRxiv · Aug 21, 2023Immunology

Distinct eosinophil subsets are modulated by agonists of the commensal-metabolite and vitamin B3 receptor GPR109A during allergic-type inflammation

R. Azzoni, K. J. Filbey, R. H. Daw, M. Z. Krauss, M. R. Hepworth, J. E. Konkel, E. M. Hessel, Y. Kannan, J. R. Grainger

The paper identifies GPR109A as a regulator of glycolytic Siglec-Fhi eosinophils during allergic inflammation, showing that GPR109A ligands reduce their frequency and activation.

bioRxiv · Aug 4, 2022 · PreprintImmunology

Genotype and Th2 cells control monocyte to tissue resident macrophage differentiation during nematode infection of the pleural cavity

C. M. Finlay, J. Parkinson, B. H. Chan, J. Ajendra, A. Chenery, A. Morrison, E. L. Houlder, S. M. Baker, B. Dickie, L. Boon, A. S. MacDonald, J. E. Konkel, D. Rückerl, J. E. Allen

This study shows that host genetics and Th2 cells influence monocyte-to-tissue-resident-macrophage differentiation during nematode infection in mice.

bioRxiv · Dec 17, 2021 · PreprintImmunology