Author

T. N. Shaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1

Frequent Co-Authors

A. D. Adamson· 1 shared A. Diez-Sanchez· 1 shared C. Chew· 1 shared C. L. Scott· 1 shared C. M. Finlay· 1 shared C. P. McEntee· 1 shared C. Smedley· 1 shared D. Rückerl· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. D. Adamson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Postnatal intestinal epithelial maturation by LSD1 controls the small intestinal immune cell composition independently from the microbiota

A. Diez-Sanchez, H. T. Lindholm, P. M. Vornewald, J. Ostrop, N. Parmar, T. N. Shaw, M. Martin-Alonso, M. J. Oudhoff

This study shows that LSD1 in intestinal epithelial cells controls immune cell composition postnatally, independent of microbiota.

bioRxiv · Sep 8, 2023Immunology

CD163 and Tim-4 identify resident intestinal macrophages across sub-tissular regions that are spatially regulated by TGF-β

I. E. Prise, V. Jayaraman, V. Kästele, R. H. Daw, K. Wemyss, H. Bridgeman, S. Tamburrano, P. Strangward, C. Chew, L. Martens, C. L. Scott, M. Guilliams, A. D. Adamson, J. E. Konkel, T. N. Shaw, J. R. Grainger

The paper identifies CD163 and Tim-4 as markers for intestinal macrophages and shows TGF-β regulates their spatial distribution in different niches.

bioRxiv · Aug 21, 2023Immunology

A subset of CD4+ effector memory T cells limit immunity to pulmonary viral infection and prevent tissue pathology via activation of latent TGFβ

C. P. McEntee, S. Houston, C. M. Finlay, S. Rossi, G. Liu, T. N. Shaw, J. Casulli, M. Fife, C. Smedley, T. S. Griffith, M. Pepper, T. Hussell, P. M. Hansbro, J.-M. Schwartz, H. Paidassi, M. A. Travis

The paper identifies a subset of CD4+ effector memory T cells that limit secondary immune responses to viral re-infection and prevent lung pathology by activating latent TGFβ.

bioRxiv · Mar 2, 2023 · PreprintImmunology

Ongoing exposure to peritoneal dialysis fluid alters resident peritoneal macrophage phenotype and activation propensity

T. E. Sutherland, T. N. Shaw, R. Lennon, S. E. Herrick, D. Rückerl

This study shows that long-term exposure to peritoneal dialysis fluid changes peritoneal macrophage function, increasing inflammation and reducing tissue resident cell survival in mice.

bioRxiv · Mar 2, 2020Immunology