Author
L. Yang
Queensland University of Technology
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2018-2026 · peak 46/yrCo-Author Collaboration Network
10 top collaborators · 38 mutual co-author links222 papers
Recent·Most cited
- ImmunologybioRxivDOI 10.7150/thno.32451
- MicrobiologybioRxiv
Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community
Y. Cheng, J. K. H. Yam, Z. Cai…·L. Yang
This study examines how Pseudomonas aeruginosa interacts with other bacteria in mixed communities, finding it dominates biofilms but not planktonic environments, with H1 type VI secretion system and biofilm factors enhancing its fitness.
DOI 10.1038/s41522-018-0076-z - ImmunologybioRxiv
MITA couples with PI3K to regulate actin reorganization during BCR activation
C. Liu, Y. Jing, D. Kang…·B. Yu
This study shows MITA regulates BCR signaling through actin reorganization via the PI3K pathway, affecting B cell differentiation and autoimmune disease.
DOI 10.1126/sciadv.aax9455 - MicrobiologybioRxiv
Systematic discovery of uncharacterized transcription factors in Escherichia coli K-12 MG1655
Y. Gao, J. T. Yurkovich, S. W. Seo…·B. O. Palsson
This study identifies and characterizes 16 uncharacterized transcription factors in E. coli K-12 MG1655 using computational prediction and experimental validation.
- PhysiologybioRxiv
Transient Overexpression of VEGF-A in Adipose Tissue Promotes Energy Expenditure via Activation of the Sympathetic Nervous System
Y. Zhao, X. Li, L. Yang…·K. Sun
This study shows that transient VEGF-A overexpression in adipose tissue activates the sympathetic nervous system, enhancing lipolysis, browning, and energy expenditure.
DOI 10.1128/mcb.00242-18 - ImmunologybioRxiv
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
K. Xu, P. Acharya, R. Kong…·McDermott
This study shows that targeting the HIV-1 fusion peptide with specific immunogens induces cross-clade neutralizing antibodies in animals.
- Cancer BiologybioRxiv
Comprehensive analysis of lung cancer pathology images to discover tumor shape features that predict survival outcome
S. Wang, A. Chen, L. Yang…·G. Xiao
This study uses a deep CNN to analyze lung cancer pathology images, identifies tumor shape features linked to survival, and develops a prognostic model validated in an independent cohort.
- Cancer BiologybioRxiv
Development and Validation of a Nomogram Prognostic Model for Small-Cell Lung Cancer Patients
S. Wang, L. Yang, B. Ci…·Y. Xie
The paper develops and validates a nomogram prognostic model for small-cell lung cancer patients using clinical data from the National Cancer Database.
DOI 10.1016/j.jtho.2018.05.037 - Cancer BiologybioRxiv
Lung Cancer Explorer (LCE): an open web portal to explore gene expression and clinical associations in lung cancer
L. Cai, S. Lin, Y. Zhou…·Y. Xie
The paper constructs a lung cancer database with gene expression and clinical data from 6,700 patients and develops an open web portal for data exploration and analysis.
DOI 10.1038/s41388-018-0588-2 - MicrobiologybioRxiv
Protein Kinase A Negatively Regulates Ca2+ signalling in Toxoplasma gondii
A. D. Uboldi, M.-L. Wilde, E. A. McRae…·C. J. Tonkin
This study shows that Protein Kinase A (PKAc1) suppresses Ca2+ signalling in Toxoplasma gondii after host cell invasion, affecting motility and infectivity.
DOI 10.1371/journal.pbio.2005642 - BiophysicsbioRxiv
From 1D sequence to 3D chromatin dynamics and cellular functions: a phase separation perspective
S. Liu, L. Zhang, H. Quan…·Y. Q. Gao
The paper identifies forest and prairie genomic domains based on CpG island density and shows their role in shaping cell-type-specific chromatin structures and genomic properties through phase separation mechanisms.
- Evolutionary BiologybioRxiv
Tracing the History of LINE and SINE Extinction in Sigmodontine Rodents
The paper traces the evolutionary history of L1 and B1 retrotransposons in sigmodontine rodents, showing that B1 extinction did not result from L1 quiescence but may have contributed to L1 extinction through competition and host pressure.
DOI 10.1186/s13100-019-0164-5