L. Zhang

This paper introduces DO-SRS, a method to visualize metabolic dynamics in living tissues by imaging deuterium incorporation into macromolecules.

The paper reports an ambient-temperature X-ray crystal structure of the Thermus thermophilus 30S ribosomal decoding complex, showing consistency with cryogenic structures but with minor conformational variations.

This paper identifies a family of RING finger proteins in C. elegans that form a signaling network regulating crossover control during meiosis.

The paper identifies forest and prairie genomic domains based on CpG island density and shows their role in shaping cell-type-specific chromatin structures and genomic properties through phase separation mechanisms.

The paper introduces SHACKTeR, a method for live cell imaging of specific chromosomal regions using CRISPR/Cas9 and TetO repeats, successfully labeling 9 loci in HCT116 cells with up to 20% efficiency.

This study shows that both motor and non-motor crosslinkers influence cytokinetic furrowing speed, promoting contraction at low levels but braking at higher levels.

The paper shows DNA methylation's long-range and local correlations reflect chromatin spatial organization across different cell types.

This paper introduces a dry method for preserving tear samples using Schirmers strips and vacuum bags, enabling room temperature storage and protein pattern preservation comparable to traditional wet methods.

The paper constructs 3D chromatin structures from Hi-C data and shows how chromatin compartments A and B are defined by distinct domain types with different loop sizes and contact patterns.