L. Zhang

This study tracks the development of a potent ZIKV-specific antibody in a convalescent human, revealing limited somatic hypermutation and high germline identity.

This study models the transmembrane potential distribution of cells under nanosecond pulsed electric fields by incorporating dielectric relaxation and electroporation effects.

The paper examines how influenza virus type and vaccination status influence nasopharyngeal microbiota composition in infected individuals and healthy controls.

The paper analyzes urinary proteomic changes in a rat brain tumor model to identify early biomarkers of tumor progression and differences between tumor growth locations.

The paper evaluates sand dune restoration methods on the Zoige Plateau, finding that sandbag and wicker with seeding improved soil conditions more than seeding alone.

This study investigates the localization and role of CK2 in Magnaporthe oryzae during growth and infection, finding it localizes to nuclei, nucleoli, septal pores, and appressoria with regulatory functions.

This study identifies TRIM21-SERPINB5 as a mechanism promoting radioresistance in nasopharyngeal carcinoma by repressing TP53 through GMPS degradation.

This study evaluates bio-bitumen made from biomass pyrolysis oil as a substitute for petro-bitumen in coating sheets, showing improved adhesion, temperature stability, mechanical strength, and flexibility.

This study shows that antibiotic resistance selection is significantly reduced in natural microbial communities compared to single-species cultures.

This study shows that IFITM3 deficiency in mice worsens influenza virus-induced cardiac dysfunction, revealing its protective role in the heart during infection.

This study identifies α-tubulin in Laodelphax striatellus as a facilitator of rice stripe virus (RSV) passage through midgut and salivary glands, enhancing horizontal transmission.

This study demonstrates that tungsten oxide nanodots exhibit strong antibacterial activity against both gram-negative and gram-positive bacteria, with enhanced efficacy under sunlight exposure and confirmed biocompatibility.

This study uses vnOCT to detect early retinal changes in a dexamethasone-induced ocular hypertension mouse model, finding that VN ratio and A-V sO2 correlate with RGC loss independent of IOP.

This study examines how biogas slurry affects soil nutrients and economic traits of Camellia oleifera fruits, finding that higher application rates improve soil fertility and fruit yield.

This study shows macrophages in pancreatic cancer release pyrimidines that inhibit gemcitabine therapy by competing with the drug for uptake and metabolism, and reducing macrophage burden improves treatment response.

The paper identifies 196 differentially expressed proteins in TGF-β1-treated lung fibroblasts and finds that VLDLR and SDC2 are upregulated in silica-exposed lungs, with knockdown reducing collagen production.

This study evaluates methods for predicting protein-protein interactions using PFN1 and P10 binding as a model, finding that SMD simulations correlate better with PMF results than conventional MD metrics.

This study identifies Cyclin B3's specific role in facilitating metaphase-to-anaphase transition in mouse oocyte meiosis I, while showing it is not required for oocyte maturation or sister chromosome segregation.

This study identifies two FDA-approved drugs, lacidipine and phenothrin, as Lassa virus entry inhibitors through high-throughput screening and mechanistic analysis.

This study shows that exogenous DCPTA improves maize drought tolerance by enhancing nitrogen metabolism during the pre-female inflorescence emergence stage.

The paper combines proteomics and machine learning to generate a high-confidence apicoplast proteome in malaria parasites, identifying 346 proteins and validating novel functions.

The paper develops an ensemble model to compare allosteric effects in ordered and disordered proteins, finding that order-order transitions are more prevalent in allostery than disorder-order transitions.

This study examines how Pseudomonas aeruginosa interacts with other bacteria in mixed communities, finding it dominates biofilms but not planktonic environments, with H1 type VI secretion system and biofilm factors enhancing its fitness.

This study identifies IFITM3 and TLR7 as endosomal factors that differentially regulate hMPV infection, with IFITM3 restricting it and TLR7 enhancing it in some strains.

The paper shows antibiotic resistance selection strength remains constant across a wide concentration range in complex microbial communities, challenging the dose-dependent assumption.

The paper tracks genome evolution in Marinimicrobia across marine environments, showing parallel shifts in genomic organization, bioenergetics, and metabolism linked to habitat transitions.

This study shows that deletion of ylmE in Streptomyces coelicolor causes severe sporulation defects, which are rescued by also deleting ylmD.

This study shows that differences in gO and UL128-131 expression levels between HCMV strains affect gH/gL complex assembly and virion infectivity, with UL128-131 repression having a stronger impact on infectivity than gO expression.

This study shows that knocking down GAS5 restores ox-LDL-induced autophagy dysfunction in endothelial cells by upregulating miR-26a.

This study shows hemolysin facilitates cytosolic LPS sensing by liberating bacterial outer membrane vesicles, leading to inflammasome activation and gut inflammation.