Author

Langchao Liang

BGI Group (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:database / resource· 3 Research Focus:gene regulatory network inference· 2 Organism:plant (other)· 2 Assay:spatial transcriptomics· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Xun XuiD· 4 shared Xiaoyu WeiiD· 3 shared An ZengiD· 2 shared Chaochao Chai· 2 shared Fang CheniD· 2 shared Gang PeiiD· 2 shared Guangyi FaniD· 2 shared Hanbo LiiD· 2 shared

Activity by Year

2020-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersDevelopmental Biology

Xun XuORCID

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Author profile →

5 papers

Recent·Most cited

Single-nucleus chromatin accessibility time course of excisional wound repair in rat skin

Chaochao Chai, Xinran Ding, Yixu Li, Langchao Liang, Runzhi Huang, Wei Zhang, Ruikang Li, Sujie Xie, Xiaoqi Zeng, Lianrui Zhang, Yue Yuan, Xiaoyu Wei, Jufang Wang, Shuai Wang, Shizhao Ji

The paper presents a time-course single-nucleus ATAC-seq dataset from rat skin wounds, revealing chromatin accessibility changes across repair phases.

bioRxiv · Oct 20, 2026 · PreprintBioinformatics

Cell Type Architecture and Positional Gene Gradients in an Adult Animal at Subcellular Resolution

Maoqin Sun, Yuxiaofei Wang, Kai Han, Lidong Guo, Yuehua Chen, Yao Li, Yaru Lin, Xiawei Liu, Zhi Huang, Qun Liu, Wenjie Guo, Rui Zhang, Wandong Zhao, Langchao Liang, Xiaoyu Wei, , An Zeng

This study reconstructs 3D spatial transcriptomic models of planarians to map cell type distribution and positional gene regulation, identifying candidate genes involved in regeneration.

bioRxiv · Feb 20, 2026 · PreprintDevelopmental Biology

4D Single-Cell Spatial Transcriptomics Reveals Dynamic Morphogenetic Gradients and Regenerative Domains in Planarians

Kai Han, Yuxiaofei Wang, Yao Li, Lidong Guo, Yue Chen, Xiawei Liu, Yaru Lin, Zhi Huang, Qun Liu, Wenjie Guo, Rui Zhang, Wandong Zhao, Langchao Liang, Xiaoyu Wei, Li Zhou, , Mengyang Xu

This study constructs a 4D spatiotemporal transcriptomic map of planarian regeneration using Stereo-seq, identifying dynamic gradients and an injury-induced regenerative zone.

GigaScience · Jan 1, 2026Peer-reviewedDevelopmental Biology

Single cell chromatin accessibility of the developmental cephalochordate

Dongsheng Chen, Zhen J. Huang, Xiangning Ding, Zaoxu Xu, Jixing Zhong, Langchao Liang, Luohao Xu, Chaochao Cai, Haoyu Wang, Jiaying Qiu, Jiacheng Zhu, Xiaoling Wang, Rong Xiang, Weiying Wu, Peiwen Ding, , Xun Xu

This study creates the first single-cell chromatin accessibility atlas of the lancelet, revealing regulatory elements and developmental trajectories.

bioRxiv · Mar 17, 2020 · PreprintDevelopmental Biology

Single cell atlas of trisomy 21 cerebral cortex

Jingxuan Zhang, Shiyou Wang, Zaoxu Xu, Xiangning Ding, Chen Li, Yonghong Zhang, Yin Chen, Jixing Zhong, Langchao Liang, Chaochao Chai, Xiaoling Wang, Rong Xiang, Jiacheng Zhu, Xiumei Lin, Peiwen Ding, , Xun Xu

This study creates the first single cell atlas of T21 cerebral cortex, identifying dysregulated genes and developing a platform for data exploration.

bioRxiv · Jan 1, 2020 · PreprintNeuroscience