Author

Yin Chen

BGI Group (China)ORCID 0000-0002-0367-4276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Dongsheng CheniD· 2 shared Fang CheniD· 2 shared Jiacheng ZhuiD· 2 shared Jixing ZhongiD· 2 shared Shida ZhuiD· 2 shared Shiyou WangiD· 2 shared Weiying WuiD· 2 shared Xiangning DingiD· 2 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Dongsheng ChenORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Unlocking the secrets of paired terminal genomic repeats utilised by the Burkholderia jumbo phage Matilda

Jessica M. Lewis, Olivia Burns, Harry Mogg, Tanaz Mistry, Yan-Jiun Lee, Peter Weigele, Eshwar Mahenthiralingam, Yin Chen, Nichollas E. Scott, Laura A. Baxter, Cristina Sousa Mesquita, Richard Stark, Trevor J. Lithgow, Jeremy J. Barr, Antonia P. Sagona

This study identifies a novel jumbo phage with a tripartite genome architecture and describes its terminal elements' role in infection.

bioRxiv · Oct 22, 2026 · PreprintMicrobiology

Strain-dependent contribution of the AcrAB-TolC efflux pump to Klebsiella pneumoniae physiology

Kirandeep Bhogal, Barbara Clough, Charlotte Emmerson, Archie Organ, Yin Chen, Michelle M. C. Buckner, Ilyas Alav

This study shows that the AcrAB-TolC efflux pump has strain-specific roles in drug resistance, biofilm formation, and virulence in Klebsiella pneumoniae.

Microbiology · Dec 19, 2025Peer-reviewedMicrobiology

Single cell atlas of trisomy 21 cerebral cortex

Jingxuan Zhang, Shiyou Wang, Zaoxu Xu, Xiangning Ding, Chen Li, Yonghong Zhang, Yin Chen, Jixing Zhong, Langchao Liang, Chaochao Chai, Xiaoling Wang, Rong Xiang, Jiacheng Zhu, Xiumei Lin, Peiwen Ding, , Xun Xu

This study creates the first single cell atlas of T21 cerebral cortex, identifying dysregulated genes and developing a platform for data exploration.

bioRxiv · Jan 1, 2020 · PreprintNeuroscience

Single cell atlas of domestic pig brain illuminates the conservation and divergence of cell types at spatial and species levels

Dongsheng Chen, Jiacheng Zhu, Jixing Zhong, Fang Chen, Xiumei Lin, Jinxia Dai, Yin Chen, Shiyou Wang, Xiangning Ding, Haoyu Wang, Jiaying Qiu, Feiyue Wang, Weiying Wu, Ping Liu, Gen Tang, , Gang Cao

This study creates the first single-cell brain atlas of domestic pigs, identifies cell types and their spatial distribution, and compares them with other species to reveal evolutionary and disease-related insights.

bioRxiv · Dec 11, 2019 · PreprintBioinformatics