Coordination of sequential RNase activities in an ancient molecular machine
Mathias Girbig, Francesca D. Naughton-Allen, Simone Prinz, Laura Andreas, Jan M. Schuller, Justin L. P. Benesch, Georg K. A. Hochberg
The paper studies the evolution of the RNA exosome, showing how an ancient active RNase evolved into a regulatory hub coordinating sequential RNase activities.
bioRxiv · Mar 18, 2026 · PreprintEvolutionary Biology