Felix Willmund

Advancing chloroplast synthetic biology through high-throughput plastome engineering of Chlamydomonas reinhardtii

This study establishes Chlamydomonas reinhardtii as a platform for chloroplast synthetic biology, enabling high-throughput engineering of plastomes and demonstrating improved biomass production through synthetic pathways.

Utilizing high resolution ribosome profiling for the global investigation of gene expression in Chlamydomonas

This study develops a high-resolution Ribo-seq protocol for Chlamydomonas to analyze translational dynamics and gene expression across nuclear and chloroplast transcripts.

Competition co-immunoprecipitation reveals interactors of the chloroplast CPN60 chaperonin machinery

The paper identifies new substrates of the chloroplast CPN60 chaperonin machinery using competition co-immunoprecipitation and mass spectrometry in Chlamydomonas reinhardtii.

Systems approaches identify the consequences ofmonosomy in somatic human cells

The paper investigates the effects of monosomy in human cells, finding that it impairs proliferation and genomic stability, with partial gene dosage compensation and ribosome biogenesis stress contributing to p53 pathway activation.

CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea

This paper introduces a CRISPR/Cas system using ribonucleoprotein complexes and telomere vectors for efficient marker-free genome editing in Botrytis cinerea, achieving high editing rates and enabling multiple edits.