Author

Lauren Dierdorff

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aarthi RamakrishnaniD· 1 shared Adele MossaiD· 1 shared Akhil UpadiD· 1 shared Baichao ZhangiD· 1 shared Chiara Fiorenzani· 1 shared Fatemeh MamashliiD· 1 shared Haifeng WangiD· 1 shared Haitao LiiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Aarthi RamakrishnanORCID

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2 papers

Recent·Most cited

Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X

Adele Mossa, Lauren Dierdorff, Jerónimo Lukin, Marta García-Forn, Wei Wang, Fatemeh Mamashli, Yeaji Park, Chiara Fiorenzani, Zeynep Akpinar, Janine Kamps, Jörg Tatzelt, Zhuhao Wu, Silvia De Rubeis

This study shows that Ddx3x mutations cause sex-specific changes in neuronal development and behavior, affecting ribosomal biogenesis, dendritic growth, and motor function in mice.

Nature Communications · May 15, 2025Peer-reviewedNeuroscience

Histone monoaminylation dynamics are regulated by a single enzyme and promote neural rhythmicity

Qingfei Zheng, Ryan M. Bastle, Shuai Zhao, Lingchun Kong, Lauren E. Vostal, Aarthi Ramakrishnan, Li Shen, Sasha L. Fulton, Haifeng Wang, Baichao Zhang, Akhil Upad, Lauren Dierdorff, Robert E. Thompson, Henrik Molina, Stephanie Stransky, , Ian S. Maze

A single enzyme, TGM2, bidirectionally controls H3 monoaminylation dynamics, which, in turn, facilitate neural rhythmicity.

bioRxiv · Dec 6, 2022 · PreprintMolecular Biology