Author

Lingchun Kong

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:ChIP-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Aarthi RamakrishnaniD· 3 shared Ian S. MazeiD· 3 shared Li SheniD· 3 shared Haitao LiiD· 2 shared Jennifer C. O’ChaniD· 2 shared Qingfei ZhengiD· 2 shared Ryan M. BastleiD· 2 shared Sasha L. FultoniD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Aarthi RamakrishnanORCID

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Author profile →

3 papers

Recent·Most cited

Quinone reductase 2 reads H3 serotonylation to support human cortical neuron development

Min Chen, Celi Yang, Xin Li, Lingchun Kong, Benjamin H. Weekley, Xiaoran Wei, Jennifer C. O’Chan, Claudia De Sanctis, Victoria Flores Almazan, David A. Vinson, Bulent Cetin, Aarthi Ramakrishnan, Li Shen, Rong Zeng, Zheng Liu, , Ian S. Maze

This study identifies QR2 as a reader of H3Q5ser, showing its role in human neuron development through transcriptional and electrophysiological effects.

bioRxiv · Mar 19, 2026 · PreprintNeuroscience

Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior

Amni Al-Kachak, Sasha L. Fulton, Giuseppina Di Salvo, Jennifer C Chan, Lorna A. Farrelly, Ashley E. Lepack, Ryan M. Bastle, Lingchun Kong, Flurin Cathomas, Emily L. Newman, Caroline Ménard, Aarthi Ramakrishnan, Polina Safovich, Yang Lyu, Herbert E. Covington, , Ian S. Maze

The paper investigates how serotonin modifies histone H3K4me3Q5ser dynamics in the dorsal raphe nucleus under stress and antidepressant exposure, showing its role in gene expression and behavior.

bioRxiv · May 4, 2023 · PreprintNeuroscience

Histone monoaminylation dynamics are regulated by a single enzyme and promote neural rhythmicity

Qingfei Zheng, Ryan M. Bastle, Shuai Zhao, Lingchun Kong, Lauren E. Vostal, Aarthi Ramakrishnan, Li Shen, Sasha L. Fulton, Haifeng Wang, Baichao Zhang, Akhil Upad, Lauren Dierdorff, Robert E. Thompson, Henrik Molina, Stephanie Stransky, , Ian S. Maze

A single enzyme, TGM2, bidirectionally controls H3 monoaminylation dynamics, which, in turn, facilitate neural rhythmicity.

bioRxiv · Dec 6, 2022 · PreprintMolecular Biology