Author

Luc Moquin

Centre intégré universitaire de santé et de services sociaux de l'Ouest-de-l’Île-de-Montréal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 2 Organism:human· 1 Assay:imaging· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1

Frequent Co-Authors

Alain P. Gratton· 2 shared Ian Omer MasséiD· 2 shared Louis De BeaumontiD· 2 shared Pedro Rosa‐NetoiD· 2 shared Alex TchungiD· 1 shared Benoît Delignat‐LavaudiD· 1 shared Brian K. ShoichetiD· 1 shared Catherine Lévesque· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersNeuroscience

Alain P. Gratton

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4 papers

Recent·Most cited

Cryo-EM structure of Alzheimer disease tau filaments with PET ligand MK-6240

Peter Kunach, Jaime Vaquer‐Alicea, Matthew S. Smith, Jim Monistrol, Robert Hopewell, Luc Moquin, Joseph Therriault, Cécile Tissot, Nesrine Rahmouni, Gassan Massarweh, Jean‐Paul Soucy, Marie‐Christine Guiot, Brian K. Shoichet, Pedro Rosa‐Neto, Marc I. Diamond, Sarah H. Shahmoradian

The paper determines the cryo-EM structure of Alzheimer's disease tau filaments bound by the PET ligand MK-6240, revealing key binding interactions that inform ligand design.

Nature Communications · Oct 1, 2024Peer-reviewedNeuroscience

Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice.

Benoît Delignat‐Lavaud, Jana Kano, Charles Ducrot, Ian Omer Massé, Sriparna Mukherjee, Nicolas Giguère, Luc Moquin, Catherine Lévesque, Samuel Burke, Raphaëlle Denis, Marie-Josée Bourque, Alex Tchung, Pedro Rosa‐Neto, Daniel Lévesque, Louis De Beaumont, Louis‐Éric Trudeau

This study shows that phasic dopamine release in mice is not essential for basic motor behaviors, as motor functions remain intact despite near-complete loss of activity-dependent dopamine release.

Nature Communications · Jul 11, 2023Peer-reviewedNeuroscience

Investigating the "two-hit hypothesis": effects of prenatal maternal immune activation and adolescent cannabis use on neurodevelopment in mice

Elisa Guma, Lani Cupo, Weiya Ma, Daniel Gallino, Luc Moquin, Alain P. Gratton, Gabriel A. Devenyi, M. Mallar Chakravarty

The paper examines if combined prenatal maternal immune activation and adolescent cannabis use lead to neurodevelopmental changes in mice, finding subtle deviations and sex-dependent effects.

Progress in Neuro-Psychopharmacology and Biological Psychiatry · Sep 21, 2022Peer-reviewedNeuroscience

In vivo cerebral microdialysis validation of the acute central glutamate response in a translational rat model of concussion combining force and rotation

Ian Omer Massé, Luc Moquin, Chloé Provost, Samuel Guay, Alain P. Gratton, Louis De Beaumont

This study validates the Wayne State weight-drop model of concussion in rats using cerebral microdialysis, showing a 3-fold increase in hippocampal glutamate levels within 10 minutes of injury.

bioRxiv · Oct 1, 2018 · PreprintNeuroscience