Author

Lumin Zhang

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Adrian LitaiD· 1 shared Aiguo LiiD· 1 shared Dionne L. DavisiD· 1 shared Ganesh GunasekaraniD· 1 shared Helena MuleyiD· 1 shared Hua SongiD· 1 shared Maria Isabel FieliD· 1 shared Mark R. GilbertiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Adrian LitaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

HIV-1 Amplifies IL-8 Response Of Human Stellate Cells To Gram-Positive Microbial Products Via H4K5 Histone Acetylation

Lumin Zhang, Rabab O. Ali, Naichaya Chamroonkul, Parissa Tabrizian, Myron Schwartz, Ganesh Gunasekaran, Thomas D. Schiano, Maria Isabel Fiel, Stephen Andrew Ward, Meena B. Bansal

This study shows HIV-1 enhances IL-8 production in HSCs in response to LTA through histone H4K5 acetylation, contributing to liver fibrosis in HIV-positive individuals.

bioRxiv · May 12, 2025 · PreprintImmunology

Targeting the sphingolipid rheostat in IDH1mut glioma alters cholesterol homeostasis and triggers apoptosis via membrane degradation

Tyrone Dowdy, Helena Muley, Adrian Lita, Aiguo Li, Tomohiro Yamasaki, Lumin Zhang, Raj Chari, Hua Song, Meili Zhang, Wei Zhang, Nicole Briceno, Dionne L. Davis, Mark R. Gilbert, Mioara Larion

This study shows that altering sphingosine levels in IDH1mut glioma cells disrupts cholesterol homeostasis, leading to apoptosis through effects on cholesterol synthesis, uptake, and efflux.

bioRxiv · Apr 26, 2024 · PreprintCancer Biology