Author

M. A. Duque-Correa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Berriman· 3 shared C. McCarthy· 2 shared D. Goulding· 2 shared R. K. Grencis· 2 shared A. Buck· 1 shared A. Coghlan· 1 shared A. E. Brown· 1 shared A. J. Reid· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

M. Berriman

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Author profile →

4 papers

Recent·Most cited

A Bioengineered Platform for Enhanced Observability of Patterned Gastrointestinal Organoid Monolayers with Bilateral Access

M. Hofer, M. A. Duque-Correa, M. P. Lutolf

This paper introduces a bioengineered platform for bilaterally accessible GI organoid monolayers, enabling improved observability and studies of epithelial dynamics and pathogen interactions.

bioRxiv · Jan 26, 2024 · PreprintBioengineering

A drug repurposing screen for whipworms informed by comparative genomics

A. Coghlan, F. A. Partridge, M. A. Duque-Correa, G. Rinaldi, S. Clare, L. Seymour, C. Brandt, T. T. Mkandawire, C. McCarthy, N. Holroyd, M. Nick, A. E. Brown, S. Tonitiwong, D. B. Sattelle, M. Berriman

This paper identifies potential anti-whipworm drugs by testing approved human drugs ex vivo and in vivo, finding limited efficacy due to pharmacokinetic challenges.

bioRxiv · Mar 2, 2023Pharmacology & Toxicology

Development of caecaloids to study host-pathogen interactions: new insights into immunoregulatory functions of Trichuris muris extracellular vesicles in the caecum

M. A. Duque-Correa, F. Schreiber, F. H. Rodgers, D. Goulding, S. Forrest, R. White, A. Buck, R. K. Grencis, M. Berriman

This paper develops a caecal organoid model to study host-pathogen interactions, revealing immunoregulatory effects of Trichuris muris extracellular vesicles on caecal epithelium.

bioRxiv · May 11, 2020Immunology

Exclusive dependence of IL-10Rα signalling on intestinal microbiota homeostasis and control of whipworm infection

M. A. Duque-Correa, N. A. Karp, C. McCarthy, S. Forman, D. Goulding, G. Sankaranarayanan, T. P. Jenkins, A. J. Reid, H. P. Browne, E. L. Cambridge, C. Ballesteros Reviriego, W. Müller, C. Cantacessi, G. Dougan, R. K. Grencis, , The 3i consortium

This study shows that IL-10R signaling in immune cells is essential for controlling whipworm infection, microbiota homeostasis, and preventing immunopathology in mice.

bioRxiv · Aug 8, 2018Immunology