Author

A. J. Taylor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:bacteria (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. J. Kelly· 2 shared A. C. Swensen· 1 shared A. E. Patterson· 1 shared A. H. van Vliet· 1 shared B. Pascoe· 1 shared C. B. Verchere· 1 shared C. M. Kobras· 1 shared D. Falush· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

D. J. Kelly

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing and alters beta cell identity in mice

Y.-C. Chen, A. J. Taylor, J. M. Fulcher, A. C. Swensen, X.-Q. Dai, M. Komba, K. L. C. Wrightson, K. Fok, A. E. Patterson, R. I. Klein-Geltink, P. E. MacDonald, W.-J. Qian, C. B. Verchere

This study shows that deleting CPE in beta cells disrupts proinsulin processing and alters beta cell identity, leading to impaired function and increased beta-cell area in mice.

bioRxiv · Oct 20, 2022 · PreprintPhysiology

A two-hit epistasis model prevents core genome disharmony in recombining bacteria

A. J. Taylor, K. Yahara, B. Pascoe, L. Mageiros, E. Mourkas, J. K. Calland, S. Puranen, M. D. Hitchings, K. A. Jolley, C. M. Kobras, S. C. Bayliss, N. J. Williams, A. H. van Vliet, J. Parkhill, M. C. Maiden, , S. K. Sheppard

The paper shows that recombination in bacteria can overcome genomic disharmony through a two-hit epistasis model, allowing beneficial gene combinations to be reinstated in new genetic backgrounds.

bioRxiv · Mar 15, 2021 · PreprintMicrobiology

The cryo-EM structure of the bacterial flagellum cap complex suggests a molecular mechanism for filament elongation.

N. S. Al-Otaibi, A. J. Taylor, D. P. Farrell, S. B. Tzokov, F. DiMaio, D. J. Kelly, J. R. C. Bergeron

The paper reports the cryo-EM structure of the Campylobacter jejuni flagellum cap complex and proposes a model for filament-cap interaction.

bioRxiv · Oct 17, 2019Microbiology