Author

S. M. Nowinski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Solmonson· 2 shared J. A. Berg· 2 shared J. Rutter· 2 shared Y. Ouyang· 2 shared A. A. Cluntun· 1 shared A. Kenaston· 1 shared B. C. Naylor· 1 shared B. Wang· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

A. Solmonson

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3 papers

Recent·Most cited

Network-aware reaction pattern recognition reveals regulatory signatures of mitochondrial dysfunction

J. A. Berg, Y. Zhou, Y. Ouyang, T. C. Waller, A. A. Cluntun, M. E. Conway, S. M. Nowinski, T. Van Ry, I. George, J. E. Cox, B. Wang, J. Rutter

The paper introduces Metaboverse, a tool for network-aware reaction pattern recognition in metabolic data, identifying regulatory signatures of mitochondrial dysfunction in lung adenocarcinoma and respiratory deficiency models.

bioRxiv · Jun 25, 2020 · PreprintBiochemistry

Mitochondrial fatty acid synthesis coordinates mitochondrial oxidative metabolism

S. M. Nowinski, A. Solmonson, S. F. Rusin, J. A. Maschek, C. L. Bensard, S. Fogarty, M.-Y. Jeong, S. Lettlova, J. A. Berg, J. T. Morgan, Y. Ouyang, B. C. Naylor, J. A. Paulo, K. Funai, J. Cox, , J. Rutter

This study shows that mitochondrial fatty acid synthesis (mtFAS) regulates electron transport chain (ETC) complexes and skeletal myoblast differentiation, linking fatty acid synthesis to oxidative metabolism.

bioRxiv · May 9, 2020Biochemistry

Identification of a fatty acid-sensitive interaction between mitochondrial uncoupling protein 3 and enoyl-CoA hydratase 1 in skeletal muscle

C. Dao, A. Kenaston, C. L. Riley, K. Hirasaka, S. Kohno, A. Solmonson, S. M. Nowinski, G. Fang, K. Fathe, M. Pfeiffer, X. Yang, T. Nikawa, E. Mills

The paper identifies a fatty acid-sensitive interaction between UCP3 and ECH1 in skeletal muscle mitochondria, enhancing FA oxidation and thermogenesis.

bioRxiv · Nov 1, 2019 · PreprintBiochemistry