Author

M. E. Griffin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 2 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

H. C. Hang· 5 shared V. Chen· 2 shared A. L. Schacht· 1 shared A. M. Keestra-Gounde· 1 shared A. Moradian· 1 shared B. Lomenick· 1 shared C. E. Curley· 1 shared D. Ercelen· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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5 shared papersCancer Biology

H. C. Hang

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Functional glycoproteomics by integrated network assembly and partitioning

M. E. Griffin, J. W. Thompson, Y. Xiao, M. J. Sweredoski, E. H. Jensen, Y. Koldobskaya, A. L. Schacht, T. D. Kim, P. Choudhry, B. Lomenick, S. D. Garbis, A. Moradian, L. C. Hsieh-Wilson

This paper introduces a systems-level approach to study O-GlcNAcylation by integrating AP-MS and chemoproteomics with network analysis, revealing both conserved and tissue-specific functions.

bioRxiv · Jun 13, 2023 · PreprintCell Biology

Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization

K. K. Jang, T. Heaney, M. London, Y. Ding, F. Yeung, D. Ercelen, Y.-H. Chen, J. Axelrad, S. Gurunathan, A. M. Keestra-Gounde, M. E. Griffin, H. C. Hang, K. Cadwell

The paper shows that overproduction of REG3 proteins in IBD flares reduces Enterococcus faecium, worsening inflammation by disrupting microbiota-immune interactions.

bioRxiv · Jan 29, 2023 · PreprintImmunology

N-arylpyrazole NOD2 agonists promote immune checkpoint inhibitor therapy

M. E. Griffin, T. Tsukidate, H. C. Hang

This study develops N-arylpyrazole NOD2 agonists that enhance immune checkpoint inhibitor therapy by specifically activating NOD2.

bioRxiv · Jan 26, 2023 · PreprintCancer Biology

Chemoproteomics of microbiota metabolites reveals small-molecule agonists for orphan receptor GPRC5A

X. Zhao, K. R. Stein, V. Chen, M. E. Griffin, H. C. Hang

The paper identifies small-molecule agonists for the orphan receptor GPRC5A using chemoproteomics of microbiota metabolites, revealing bacterial sources and key residues involved in ligand binding.

bioRxiv · Dec 16, 2021 · PreprintBiochemistry

RecT recombinase expression enables efficient gene editing in Enterococcus

V. Chen, M. E. Griffin, H. C. Hang

This paper demonstrates that expressing RecT recombinase in Enterococcus species significantly improves gene editing efficiency using recombineering techniques.

bioRxiv · Sep 1, 2020Microbiology

Enterococcus peptidoglycan remodeling promotes immune checkpoint inhibitor therapy

M. E. Griffin, J. Espinosa, J. L. Becker, J. K. Jha, G. R. Fanger, H. C. Hang

The paper shows that Enterococcus species enhance immune checkpoint inhibitor therapy by remodeling peptidoglycan and activating Nod2.

bioRxiv · Aug 20, 2020Cancer Biology

Prolonged oral coenzyme Q10-β-cyclodextrin supplementation increases plasma CoQ10 concentration and skeletal muscle complex I+III activity in young, untrained healthy Thoroughbreds

M. F. Rooney, C. E. Curley, J. Sweeney, M. E. Griffin, R. K. Porter, E. W. Hill, L. M. Katz

bioRxiv · Oct 25, 2019 · PreprintBiochemistry