Author

C. Pitzalis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 5 Organism:human· 5 Assay:scRNA-seq· 4 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:deep learning· 2

Frequent Co-Authors

S. Raychaudhuri· 4 shared A. Filer· 3 shared D. A. Rao· 3 shared D. L. Boyle· 3 shared F. Zhang· 3 shared G. S. Firestein· 3 shared K. Wei· 3 shared L. T. Donlin· 3 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

S. Raychaudhuri

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Spatial mapping of rheumatoid arthritis synovial niches reveals specific macrophage networks associated with response to therapy

J. De Lima, M.-A. Boutet, O. Bortolotti, L.-A. Chepeaux, Y. Glasson, A.-S. Dume, A. Le Pluart, A. Nerviani, L. Fossati-Jimack, H.-A. Michaud, J. Guicheux, B. Le Goff, C. Pitzalis, G. Courties, F. Apparailly, F. Blanchard

The paper uses spatial profiling to identify macrophage networks in RA synovium linked to treatment response.

bioRxiv · Oct 20, 2023Immunology

Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium

G. S. Dunlap, A. Wagner, N. Meednu, F. Zhang, A. H. Jonsson, K. Wei, S. Sakaue, A. Nathan, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (A, V. P. Bykerk, L. T. Donlin, S. M. Goodman, G. S. Firestein, D. L. Boyle, V. M. Holers, , J. Anolik

This study uses single-cell antigen receptor profiling to identify clonal relationships and functional states of T and B cells in RA synovium.

bioRxiv · Mar 18, 2023 · PreprintImmunology

Single cell analysis of RA synovial B cells reveals a dynamic spectrum of ectopic lymphoid B cell activation and hypermutation characterized by NR4A nuclear receptor expression

N. Meednu, J. Rangel-Moreno, F. Zhang, K. Escalera-Rivera, E. Corsiero, E. Prediletto, E. Dicarlo, S. Goodman, L. Donlin, S. Raychaudhuri, M. Bombardieri, C. Pitzalis, D. Orange, AMP (RA/SLE) netwrok, A. McDavid, J. H. Anolik

The paper identifies NR4A-expressing B cells in RA synovium that show activated transcriptomic profiles and somatic hypermutation, suggesting in situ differentiation and roles in ELS and immune responses.

bioRxiv · May 14, 2021 · PreprintImmunology

Defining Inflammatory Cell States in Rheumatoid Arthritis Joint Synovial Tissues by Integrating Single-cell Transcriptomics and Mass Cytometry

F. Zhang, K. Wei, K. Slowikowski, C. Y. Fonseka, D. A. Rao, S. Kelly, S. M. Goodman, D. Tabechian, L. B. Hughes, K. Salomon-Escoto, G. F. M. Watts, W. Apruzzese, D. J. Lieb, D. L. Boyle, A. M. Mandelin, , S. Raychaudhuri

The paper identifies key inflammatory cell states in RA synovial tissues using integrated single-cell and mass cytometry data from patient samples.

bioRxiv · Jun 20, 2018Immunology

High dimensional analyses of cells dissociated from cryopreserved synovial tissue

L. T. Donlin, D. A. Rao, K. Wei, K. Slowikowski, M. J. McGeachy, J. D. Turner, N. Meednu, F. Mizoguchi, M. Gutierrez-Arcelus, D. J. Lieb, J. Keegan, K. Muskat, J. Hillman, C. Rozo, E. Ricker, , M. B Brenner

This paper establishes a protocol for dissociating cryopreserved synovial tissue to obtain viable cells with preserved transcriptomes and surface markers, enabling high-dimensional analysis of rheumatoid arthritis pathology.

bioRxiv · Mar 19, 2018Immunology