M. Jasinski

A key residue of the extracellular gate provides quality control contributing to ABCG substrate specificity

The paper shows that mutation of L704 in ABCG36 affects substrate specificity by altering transport of IBA and CLX, with molecular dynamics supporting a quality control role.

Identification of tumor-specific MHC ligands through improved biochemical isolation and incorporation of machine learning

This paper improves the isolation of tumor-specific MHC ligands through hydrophobicity and post-translational modification considerations and introduces a machine learning model for predicting MHC ligand presentation.

ARDitox: platform for the prediction of TCRs potential off-target binding

ARDitox predicts TCR off-target binding using computational immunology and AI, identifying cross-reactive epitopes in cancer and viral targets.

Medicago truncatula ABCG40 is a cytokinin importer that negatively regulates lateral root density and nodule number

This study identifies MtABCG40 as a cytokinin importer in Medicago truncatula that reduces lateral root density and nodule number by affecting CK signaling and auxin response.

Restriction of access to the central cavity is a major contributor to substrate selectivity in plant ABCG transporters

The paper identifies a narrow access path in MtABCG46 that contributes to substrate selectivity in plant ABCG transporters.

A phospho-switch provided by LRR receptor-like kinase, ALK1/QSK1/KIN7, prioritizes ABCG36/PEN3/PDR8 transport toward defense

This study identifies a phospho-switch mechanism involving ALK1 and ABCG36 that prioritizes defense-related transport over growth in Arabidopsis.

Identification of an isoflavonoid transporter required for the nodule establishment of the Rhizobium-Fabaceae symbiotic interaction

The paper identifies LaMATE2 as a transporter required for isoflavonoid release and nodule formation in white lupin during symbiosis with rhizobia.

A conserved D/E-P motif in the nucleotide binding domain of plant ABCB/PGP-type ABC transporters defines their auxin transport capacity

The paper identifies a conserved D/E-P motif in plant ABCB transporters that defines their auxin transport capacity and shows its role in interaction with TWD1.