M. Kogawa

A combination of two-enzyme system and enzyme engineering improved the activity of a new PET hydrolase identified from soil bacterial genome

The paper identifies a novel PET hydrolase from soil bacteria, enhances its activity with CALB and protein engineering, achieving 95.5% PET degradation.

Male-killing-associated bacteriophage WO identified from comparisons of Wolbachia endosymbionts of Homona magnanima

The paper identifies a male-killing-associated bacteriophage WO in Wolbachia strains of Homona magnanima and proposes a mechanism for male-killing evolution.

Targeted single-cell genomics reveals novel host adaptation strategies of the symbiotic bacteria Endozoicomonas in Acropora tenuis coral

This study uses single-cell genomics to analyze Endozoicomonas bacteria in Acropora tenuis corals, revealing host-adaptive genes that may enhance coral stress tolerance.

Revealing within-species diversity in uncultured human gut bacteria with single-cell long-read sequencing

This study develops a single-cell long-read sequencing workflow to generate complete bacterial genomes from uncultured human gut bacteria, revealing structural diversity and phage insertions within species.

Single-cell metabolite detection and genomics reveals uncultivated talented producer

This study identifies an uncultivated bacterium as a producer of antifungal metabolites using Raman microscopy and single-cell sequencing in a sponge microbiome.

Recovery of high-quality assembled genomes via metagenome binning guided with single-cell amplified genomes

This paper introduces MetaSAG, a method using single-cell genomes to improve metagenome binning, resulting in higher quality and strain-resolved microbial genomes from complex communities.

Single-cell genomics of uncultured bacteria reveals dietary fiber responders in the mouse gut microbiota

This study develops a single-cell genomic sequencing technique to identify bacterial responders to dietary fiber in the mouse gut microbiota, revealing metabolic pathways and functional lineages involved in fiber fermentation.