Author

S. Sakurai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Ecology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

T. Yamamoto· 2 shared A. Matsushita· 1 shared A. Shimizu· 1 shared H. Bono· 1 shared H. Mabashi-Asazuma· 1 shared H. Murakami· 1 shared H. Oshiumi· 1 shared H. Sakurai· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersPathology

T. Yamamoto

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Author profile →

4 papers

Recent·Most cited

A combination of two-enzyme system and enzyme engineering improved the activity of a new PET hydrolase identified from soil bacterial genome

H. Mabashi-Asazuma, M. Hirai, S. Sakurai, K. Ide, M. Kogawa, A. Matsushita, M. Hosokawa, S. Tsuda

The paper identifies a novel PET hydrolase from soil bacteria, enhances its activity with CALB and protein engineering, achieving 95.5% PET degradation.

bioRxiv · Feb 1, 2024Bioengineering

Hit-and-run silencing of endogenous DUX4 by targeting DNA hypomethylation on D4Z4 repeats in facioscapulohumeral muscular dystrophy

M. Sasaki-Honda, T. Jonouchi, M. Arai, J. He, K. Okita, S. Sakurai, T. Yamamoto, H. Sakurai

This study uses hit-and-run silencing to suppress DUX4 in FSHD patient-derived iPSCs by targeting DNA hypomethylation on D4Z4 repeats, achieving sustained suppression for at least two weeks.

bioRxiv · Apr 12, 2022 · PreprintPathology

Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats

K. Oka, S. Fujioka, Y. Kawamura, Y. Komohara, T. Chujo, K. Sekiguchi, Y. Yamamura, Y. Oiwa, N. Omamiuda-Ishikawa, S. Komaki, Y. Sutoh, S. Sakurai, K. Tomizawa, H. Bono, A. Shimizu, , K. Miura

This study shows naked mole-rats (NMRs) resist chemical carcinogenesis through reduced inflammatory responses linked to necroptosis deficiency.

bioRxiv · Oct 21, 2021Cancer Biology

Quantitative monitoring of multispecies fish environmental DNA using high-throughput sequencing

M. Ushio, H. Murakami, R. Masuda, T. Sado, M. Miya, S. Sakurai, H. Yamanaka, T. Minamoto, M. Kondoh

This study quantifies fish eDNA copy numbers using internal standards and high-throughput sequencing, showing strong correlation with qPCR and enabling efficient biodiversity monitoring.

bioRxiv · Dec 7, 2017Ecology