Author

M. Kuiper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Flobak· 2 shared A. Laegreid· 1 shared A. Martinez del Val· 1 shared B. M. Collins· 1 shared B. P. Howden· 1 shared B. Winnen· 1 shared C. A. McDevitt· 1 shared E. Tsirvouli· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. Flobak

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deciphering molecular mechanisms of synergistic growth reduction in kinase inhibitor combinations

E. Tsirvouli, A. Martinez del Val, L. Thommesen, A. Laegreid, M. Kuiper, J. V. Olsen, A. Flobak

This study investigates synergistic effects of kinase inhibitor combinations by analyzing phosphoproteomics and transcriptomics data to identify molecular mechanisms and pathway interactions.

bioRxiv · Mar 12, 2024 · PreprintCancer Biology

A reference model for the combination of an arbitrary number of drugs: A generalization of the Bliss independence model

W. De Mulder, M. Kuiper, A. Flobak

This paper generalizes the Bliss independence model to allow arbitrary maximal effects for dose-response curves in drug combinations while maintaining statistical independence assumptions.

bioRxiv · May 7, 2019 · PreprintCancer Biology

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

I. R. Monk, N. Shaikh, S. L. Begg, M. Gajdiss, J. Y. H. Lee, S. J. Pidot, T. Seemann, M. Kuiper, B. Winnen, R. Hvorup, B. M. Collins, G. Bierbaum, B. P. Howden, C. A. McDevitt, G. F. King, T. P. Stinear

The paper identifies zinc binding to the WalK histidine kinase's PAS domain as a negative regulator of the WalKR two-component system in Staphylococcus aureus.

bioRxiv · Aug 31, 2018Microbiology