G. F. King

NaV1.7 targeted fluorescence imaging agents for nerve identification during intraoperative procedures

This paper develops fluorescent imaging agents targeting NaV1.7 to improve nerve visualization during surgery, demonstrating effectiveness in non-human primates.

High-content fluorescence bioassay to investigate pore formation, ion channel modulation and cell membrane lysis induced by venoms

This paper develops a fluorescence-based high-content assay to identify venom-induced cellular activities like membrane lysis, pore formation, and ion channel modulation across different cell types.

Holistic profiling of the venom from the lethal spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

This study profiles the venom of Phoneutria nigriventer using proteomics and ion channel assays to identify neuroactive peptides and their potential therapeutic applications.

The voltage-gated sodium channel NaV1.7 underlies endometriosis-associated chronic pelvic pain

This study shows that inhibiting NaV1.7 reduces endometriosis-associated chronic pelvic pain without affecting normal sensation.

Heterodimeric insecticidal peptide provides new insights into the molecular and functional diversity of ant venoms

This study identifies a potent insecticidal heterodimeric peptide from ant venom, showing enhanced stability and insecticidal activity compared to its homodimers.

Structural venomics: evolution of a complex chemical arsenal by massive duplication and neofunctionalization of a single ancestral fold

The paper investigates the evolution of spider venom complexity by analyzing the structural and genetic basis of disulfide-rich peptides in the Australian funnel-web spider.

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

The paper identifies zinc binding to the WalK histidine kinase's PAS domain as a negative regulator of the WalKR two-component system in Staphylococcus aureus.