Author

M. Michino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:Arabidopsis· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

D. J. Huggins· 2 shared A. Jennings· 1 shared A. Sato· 1 shared A. W. Stamford· 1 shared C. Kambach· 1 shared C. S. Jiang· 1 shared C. Steegborn· 1 shared D. Tomita· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPharmacology & Toxicology

D. J. Huggins

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Next Generation Neuropeptide Y Receptor Small Molecule Agonists Inhibit Mosquito Biting Behavior

E. V. Zeledon, L. A. Baxt, T. A. Khan, M. Michino, M. Miller, D. J. Huggins, C. S. Jiang, L. B. Vosshall, L. B. Duvall

The paper identifies three new small molecule agonists for NPYLR7 that suppress mosquito blood feeding at lower doses than previous compounds.

bioRxiv · Feb 28, 2024Pharmacology & Toxicology

External fertilization is orchestrated by a pH-regulated soluble adenylyl cyclase controlling sperm motility and chemotaxis

H. G. Koerschen, H. Hamzeh, R. Pascal, L. Alvarez, W. Boenigk, N. Kaur, L. Levin, J. Buck, C. Kambach, M. Michino, A. Jennings, A. Sato, R. Seifert, T. Struenker, C. Steegborn, U. B. Kaupp

This paper identifies a pH-regulated soluble adenylyl cyclase in non-mammalian sperm that controls motility and chemotaxis, revealing evolutionary adaptations to aquatic environments.

bioRxiv · Jun 18, 2021 · PreprintBiophysics

A chemical strategy toward novel brain-penetrant EZH2 inhibitors

R. Liang, D. Tomita, Y. Sasaki, J. Ginn, M. Michino, D. J. Huggins, L. Baxt, S. Kargman, M. Shahid, K. Aso, M. Duggan, A. W. Stamford, E. DeStanchina, N. Liverton, P. T. Meinke, , R. E. Phillips

This paper identifies a chemical strategy to develop brain-penetrant EZH2 inhibitors and reports two novel compounds with improved properties.

bioRxiv · Jun 10, 2021Cancer Biology