M. N. Price

High-throughput genetics enables identification of nutrient utilization and accessory energy metabolism genes in a model methanogen

This paper uses high-throughput genetics to identify nutrient utilization and accessory energy metabolism genes in the methanogen Methanococcus maripaludis.

Many Families of Lids for TonB-dependent Transporters in Bacteroides

The paper identifies six families of putative lids for non-SusC TonB-dependent transporters in Bacteroides, showing their role in receptor function.

Barcoded overexpression screens in gut Bacteroidales identify genes with new roles in carbon utilization and stress resistance

The paper identifies new gene functions in gut Bacteroidales using a barcoded overexpression screen, revealing roles in carbon utilization and stress resistance.

GapMind for Carbon Sources: Automatedannotations of catabolic pathways

GapMind for carbon sources annotates catabolic pathways in bacterial and archaeal genomes using genetic data and curated information, improving coverage and confidence in pathway predictions.

Systematic Discovery of Pseudomonad Genetic Factors Involved in Sensitivity to Tailocins

This study identifies genetic factors in pseudomonads that influence sensitivity to tailocins using transposon libraries and genomics.

Large-scale Genetic Characterization of a Model Sulfate Reducing Bacterium

This study characterizes the genetic essentiality and conditional phenotypes of Desulfovibrio vulgaris Hildenborough using a transposon mutant library under various metabolic and stress conditions.

High-throughput mapping of the phage resistance landscape in E. coli

This study maps host genetic determinants of phage resistance in E. coli using high-throughput genetic screens, identifying both known and novel resistance factors across 14 phages.

Four Families of Folate-independent Methionine Synthases

The paper identifies four families of folate-independent methionine synthases and characterizes their methyl donor requirements and distribution across different organisms.

Selective carbon sources influence the end-products of microbial nitrate respiration

The paper investigates how different carbon sources affect the end-products of nitrate respiration in microbial communities from diverse environments.

Large-scale chemical-genetics of the human gut bacterium Bacteroides thetaiotaomicron

This study systematically measures mutant phenotypes for genes in Bacteroides thetaiotaomicron to uncover gene functions and improve understanding of gut microbiota physiology.

Oxidative pathways of deoxyribose and deoxyribonate catabolism

The paper identifies novel oxidative pathways for deoxyribose and deoxyribonate catabolism in bacteria using genome-wide mutant fitness assays and genetic evidence.

Defining the toxicity limits on microbial range in a metal-contaminated aquifer

The paper identifies toxic inorganic ions that inhibit sensitive microorganisms and favor Rhodanobacter in a metal-contaminated aquifer.

Dub-seq: dual-barcoded shotgun expression library sequencing for high-throughput characterization of functional traits

Dub-seq enables high-throughput overexpression screens in E. coli by combining shotgun expression libraries with DNA barcode sequencing to identify genes with gain-of-function phenotypes.

Validating Regulatory Predictions from Diverse Bacteria with Mutant Fitness Data

The paper validates regulatory predictions from bacterial transcription factors using mutant fitness data, identifying significant cofitness for 158 TFs across 24 bacteria.