Author

M. Niederweis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. L. Rosario· 1 shared A. M. Raczkowski· 1 shared A. Mitra· 1 shared A. R. Reddi· 1 shared B. Carragher· 1 shared B. Kloss· 1 shared B. L. Spencer· 1 shared C. S. Potter· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. L. Rosario

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Control of subunit stoichiometry in single-chain MspA nanopores

M. Pavlenok, L. Yu, D. Herrmann, M. Wanunu, M. Niederweis

This study converts octameric MspA into single-chain pores to improve DNA sequencing accuracy by enabling controlled subunit stoichiometry and pore geometry.

bioRxiv · Sep 25, 2021Biophysics

A type VII secretion system in Group B Streptococcus mediates cytotoxicity and virulence

B. L. Spencer, U. Tak, J. C. Mendonca, P. E. Nagao, M. Niederweis, K. S. Doran

This study identifies a type VII secretion system in Group B Streptococcus that contributes to virulence and cytotoxicity through the WXG100 effector EsxA.

bioRxiv · Jun 15, 2021Microbiology

The terminal heme synthetic enzyme, Coproheme Decarboxylase, coordinates heme synthesis and uptake in response to iron in Mycobacteria

R. K. Donegan, J. Copeland, S. Edgha, G. Brown, O. F. Hale, A. Mitra, H. Yang, H. A. Dailey, M. Niederweis, P. Jain, A. R. Reddi

This study identifies Coproheme Decarboxylase (ChdC) as a regulator of heme synthesis and uptake in Mycobacterium tuberculosis, showing it controls heme bioavailability and iron acquisition in response to iron availability.

bioRxiv · May 10, 2021 · PreprintMicrobiology

Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria

Y. Z. Tan, L. Zhang, J. Rodrigues, R. B. Zheng, S. I. Giacometti, A. L. Rosario, B. Kloss, V. P. Dandey, H. Wei, R. Brunton, A. M. Raczkowski, D. Athayde, M. J. Catalao, M. Pimentel, O. B. Clarke, , F. Mancia

The paper presents the cryo-EM structure of AftD from M. abscessus and shows its interaction with ACP, revealing potential regulatory mechanisms.

bioRxiv · Dec 22, 2019Biochemistry