Author

M. P. Rubinstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

C. M. Paulos· 3 shared H. M. Knochelmann· 3 shared M. M. Wyatt· 3 shared A. M. Rivera-Reyes· 2 shared A. S. Smith· 2 shared C. J. Dwyer· 2 shared D. M. Neskey· 2 shared G. O. Rangel Rivera· 2 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

C. M. Paulos

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Discovering tumor-reactive T-cell receptors through single-cell sequencing of tumor-infiltrating lymphocytes

E. Gottschalk, B. A. Aksoy, P. Aksoy, M. Swiderska-Syn, C. Mart, L. Macpherson, M. Romeo, A. Smith, H. Knochelmann, C. Paulos, C. Timmers, J. Wrangle, M. P. Rubinstein, J. Hammerbacher

The paper uses single-cell sequencing of tumor-infiltrating lymphocytes to identify and validate novel tumor-reactive T-cell receptors in a mouse model.

bioRxiv · Nov 30, 2021 · PreprintImmunology

B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity

A. S. Smith, H. M. Knochelmann, M. M. Wyatt, G. O. Rangel Rivera, A. M. Rivera-Reyes, C. J. Dwyer, D. M. Neskey, M. P. Rubinstein, B. Liu, J. E. Thaxton, E. Bartee, C. M. Paulos

This study shows that CpG-mediated expansion with B cells enhances CD8+ T cell tumor immunity by inducing a unique proteomic signature and specific surface markers.

bioRxiv · Mar 16, 2021Immunology

Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies

H. M. Knochelmann, A. M. Rivera-Reyes, M. M. Wyatt, A. S. Smith, R. Chamness, C. J. Dwyer, M. Bobian, G. O. Rangel Rivera, J. D. Horton, M. Lilly, M. P. Rubinstein, D. M. Neskey, C. M. Paulos

The paper expands murine tumor-infiltrating lymphocytes ex vivo in IL-2 and compares their phenotypes to human TILs from oral cavity cancer patients.

bioRxiv · Feb 4, 2021Immunology

Identification of human CD4+ T cell populations with distinct antitumor activity

M. H. Nelson, H. M. Knochelmann, S. R. Bailey, L. W. Huff, J. S. Bowers, K. Majchrzak, M. M. Wyatt, M. P. Rubinstein, S. Mehrotra, M. I. Nishimura, K. Armeson, P. G. Giresi, M. J. Zilliox, H. E. Broxmeyer, C. M. Paulos

The paper identifies human CD4+ T cell populations with distinct antitumor activity, showing CD26high T cells are epigenetically and transcriptionally different from Th17 cells and are more effective in tumor therapy.

bioRxiv · Dec 31, 2019Immunology