Author

M. Q. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

G. Niu· 2 shared J. Gao· 2 shared M. Shi· 2 shared Y. Chen· 2 shared A. J. Aguirre· 1 shared A. L. Moriera· 1 shared A. S. Patel· 1 shared A. Sharifi· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

G. Niu

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer

X. Tong, A. S. Patel, E. Kim, H. Li, Y. Chen, S. Li, S. Liu, J. Dilly, K. S. Kapner, Y. Xue, L. Hover, S. Mukhopadhyay, F. Sherman, K. Mynzdar, Y. Gao, , H. Ji

The paper identifies adeno-to-squamous transition (AST) as a mechanism of resistance to KRAS inhibitors in LKB1 mutant lung cancer and links KRT6A expression to poor patient outcomes.

bioRxiv · Sep 7, 2023 · PreprintCancer Biology

Enterococcus faecalis strains with compromised CRISPR-Cas defense emerge under antibiotic selection for a CRISPR-targeted plasmid

W. Huo, V. J. Price, A. Sharifi, M. Q. Zhang, K. L. Palmer

This study shows that antibiotic selection leads to compromised CRISPR-Cas defense in E. faecalis, enabling enhanced acquisition of antibiotic resistance plasmids.

bioRxiv · May 10, 2023 · PreprintMicrobiology

Quantifying phase separation property of chromatin associated proteins under physiological conditions using anti-1,6-hexanediol index

M. Shi, K. You, T. Chen, C. Hou, Z. Liang, M. Liu, J. Wang, T. Wei, J. Qin, Y. Chen, M. Q. Zhang, T. Li

The paper quantifies the phase separation properties of chromatin-associated proteins using an anti-1,6-hexanediol index and shows functional correlations with chromatin organization.

bioRxiv · Dec 7, 2020Cell Biology

Imaging chromatin interactions at sub-kilobase resolution Via Tn5-FISH

X. Zhang, J. Niu, G. Li, Q. Dai, D. Jin, J. Gao, M. Q. Zhang

This paper introduces Tn5-FISH, a method to visualize chromatin interactions at sub-kilobase resolution and validate results from 3C-derivative methods.

bioRxiv · Apr 7, 2019 · PreprintCell Biology

Rare non-synonymous germline mutations systematically define the risk of triple negative breast cancer

M. Yang, F. Y. Fan, Z.-Y. Wu, Z. Feng, Q. Zhang, S. Han, X. Li, T. Zhu, M. Cheng, J. Xu, C. Yang, H. Gao, C. Zhang, G. Tan, M. Q. Zhang, , K. Wang

This paper identifies rare germline mutations associated with triple-negative breast cancer risk using a machine learning approach and shows improved risk prediction compared to existing methods.

bioRxiv · Feb 26, 2019 · PreprintCancer Biology

Lipid rafts increase to facilitate ectoderm lineage specification of differentiating embryonic stem cells

C. Xu, B. Cao, Y.-d. Huo, G. Niu, M. Q. Zhang, Z.-l. Mai, X.-b. Lu, H.-b. Niu, D.-n. Chen, Y.-x. Ni

The paper shows lipid rafts increase during mESC differentiation and support ectoderm lineage specification and pluripotency exit.

bioRxiv · Jan 21, 2019 · PreprintCell Biology