Author

M. R. Lyons-Cohen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

M. Y. Gerner· 2 shared B. E. Olin· 1 shared B. H. Gern· 1 shared C. L. Paz-Stoltzfus· 1 shared C. R. Plumlee· 1 shared C. R. Stoltzfus· 1 shared D. J. Erle· 1 shared D. Raftery· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

M. Y. Gerner

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Author profile →

3 papers

Recent·Most cited

Prolonged T cell - DC macro-clustering within lymph node microenvironments initiates Th2 cell differentiation in a site specific manner

M. R. Lyons-Cohen, E. Shamskhou, M. Y. Gerner

The paper shows that Th2 cell differentiation in lymph nodes depends on site-specific macro-clustering of T cells and dendritic cells, driven by differences in cDC2 activation states.

bioRxiv · Jul 7, 2023 · PreprintImmunology

CytoMAP: a spatial analysis toolbox reveals features of myeloid cell organization in lymphoid tissues

C. R. Stoltzfus, J. Filipek, B. H. Gern, B. E. Olin, J. M. Leal, M. R. Lyons-Cohen, J. Huang, C. L. Paz-Stoltzfus, C. R. Plumlee, T. Pöschinger, K. B. Urdahl, M. Perro, M. Y. Gerner

CytoMAP is a spatial analysis toolbox that identifies cellular networks and tissue organization features in lymphoid tissues using 2D/3D imaging data.

bioRxiv · Nov 21, 2019Immunology

Detection of succinate by intestinal tuft cells triggers a type 2 innate immune circuit

M. S. Nadjsombati, J. W. McGinty, M. R. Lyons-Cohen, J. L. Pollack, G. A. Nagana Gowda, D. J. Erle, R. M. Locksley, D. Raftery, J. von Moltke

The paper identifies succinate as a ligand that activates intestinal tuft cells to initiate type 2 immune responses, linking microbial metabolism to immune sensing.

bioRxiv · Apr 29, 2018Immunology