Author

M. S. Nadjsombati

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. von Moltke· 2 shared A. Bendesky· 1 shared A. W. Goldrath· 1 shared D. J. Erle· 1 shared D. L. Jones· 1 shared D. Raftery· 1 shared E. A. Kennedy· 1 shared G. A. Nagana Gowda· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

J. von Moltke

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3 papers

Recent·Most cited

Genetic mapping reveals Pou2af2-dependent tuning of tuft cell differentiation and intestinal type 2 immunity

M. S. Nadjsombati, N. Niepoth, L. M. Webeck, E. A. Kennedy, D. L. Jones, M. T. Baldridge, A. Bendesky, J. von Moltke

The paper identifies Pou2af2 isoform usage as a regulator of tuft cell differentiation and intestinal type 2 immunity through genetic mapping in mice.

bioRxiv · Oct 19, 2022 · PreprintImmunology

Ubiquitin specific protease 1 expression and function in T cell immunity

K. D. Omilusik, M. S. Nadjsombati, T. M. Yoshida, L. A. Shaw, J. Goulding, A. W. Goldrath

This study investigates the role of Usp1 in regulating Id2 and Id3 proteins in T cells, showing its impact on memory cell maintenance and secondary immune responses.

bioRxiv · Apr 8, 2021Immunology

Detection of succinate by intestinal tuft cells triggers a type 2 innate immune circuit

M. S. Nadjsombati, J. W. McGinty, M. R. Lyons-Cohen, J. L. Pollack, G. A. Nagana Gowda, D. J. Erle, R. M. Locksley, D. Raftery, J. von Moltke

The paper identifies succinate as a ligand that activates intestinal tuft cells to initiate type 2 immune responses, linking microbial metabolism to immune sensing.

bioRxiv · Apr 29, 2018Immunology