Author

Marco de Simone

Genentech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Abbas NaziriD· 1 shared Alejandro ToboniD· 1 shared Aviv RegeviD· 1 shared Bence DánieliD· 1 shared Berta Marcó de la CruziD· 1 shared Carlo Emanuele VillaiD· 1 shared Cristina CheroniiD· 1 shared Danilo MaddaloiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Abbas NazirORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Spatiotemporal profiling reveals the role of inflammatory niche in driving prostate cancer

Abbas Nazir, Hanchen Wang, Ziyu Lu, Jeffrey Lau, Frank Peale, Rajiv Jesudason, Kelli A. Connolly, Žaneta Andrusivová, Julia Lau, Sarah Gierke, Linna Peng, Sara Chan, Jian Jiang, Sandra Rost, Eric Lubeck, , Aviv Regev

This study uses single-cell and spatial profiling to show that inflammatory signals from macrophages and fibroblasts drive CD8 T cell exhaustion and resistance to immune checkpoint blockade in prostate cancer.

bioRxiv · Apr 22, 2026 · PreprintCancer Biology

Human cortical organoids expose a differential function of GSK3 on direct and indirect neurogenesis

Alejandro Tobon, Carlo Emanuele Villa, Cristina Cheroni, Sebastiano Trattaro, Nicolò Caporale, Paola Conforti, Raffaele Iennaco, Maria Lachgar-Ruiz, Marco Tullio Rigoli, Berta Marcó de la Cruz, Pietro Lo Riso, Erika Tenderini, Flavia Troglio, Marco de Simone, Isabel Liste, , Giuseppe Testa

This study uses human cortical organoids to show that GSK3 inhibition affects progenitor proliferation and tissue architecture, with specific impacts on outer radial glia and astrogenic lineage.

bioRxiv · Mar 4, 2019 · PreprintDevelopmental Biology