Author

Michael R Jackson

Sanford Burnham Prebys Medical Discovery Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Eduard A. SergienkoiD· 2 shared Andrey A. BobkoviD· 1 shared Bobby BeaumontiD· 1 shared Bradley T. HymaniD· 1 shared Caiqin WangiD· 1 shared Camryn Crotty· 1 shared Chen-Ting Ma· 1 shared Erica Keane RiveraiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Eduard A. SergienkoORCID

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Author profile →

2 papers

Recent·Most cited

High-Throughput Screening Identifies Small-Molecule Inhibitors of the Tau-LRP1 Interaction

Caiqin Wang, Chen-Ting Ma, Camryn Crotty, Fu‐Yue Zeng, Andrey A. Bobkov, Jonathan A. Covel, Erica Keane Rivera, Eduard A. Sergienko, Kenneth S. Kosik, Steven H. Olson, Michael R Jackson, Jennifer N. Rauch

This study identifies small-molecule inhibitors of the tau-LRP1 interaction using biochemical assays and high-throughput screening, showing reduced tau uptake in cellular assays.

bioRxiv · Sep 2, 2026 · PreprintBiochemistry

Utilizing a cell culture based novel cellular thermal shift assay to understand the isoform-dependent thermal stability of ApoE variants

Rosemary J. Jackson, Steven E. Dierksmeier, Maryam A. Nishtar, Jonah C Meltzer, Frieda Balduin, Bobby Beaumont, Zhanyun Fan, Eduard A. Sergienko, Steve Olson, Michael R Jackson, Bradley T. Hyman

The paper develops BiTSA, a bioluminescence-based thermal stability assay, to characterize isoform-dependent thermal stability of ApoE variants in living cells and confirms that ApoE4 is less stable than ApoE3 in native tissue.

bioRxiv · Jun 11, 2026 · PreprintNeuroscience