Author

N. E. Vangos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

H.-S. Seo· 3 shared S. Dhe-Paganon· 3 shared E. A. Geffken· 2 shared J. A. Marto· 2 shared N. S. Gray· 2 shared A. Yang· 1 shared B. J. Pinch· 1 shared B. Nabet· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

H.-S. Seo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Development of PRPK Directed Phthalimides

H.-S. Seo, T. Mizutani, T. Hideshima, N. E. Vangos, T. Zhang, K. C. Anderson, N. S. Gray, S. Dhe-Paganon

This paper develops PRPK-directed phthalimides based on pomalidomide, identifies a potent and selective PRPK binder, and highlights distinct binding mechanisms compared to cereblon.

bioRxiv · Nov 30, 2021 · PreprintBiochemistry

Sulfopin, a selective covalent inhibitor of Pin1, blocks Myc-driven tumor initiation and growth in vivo

C. Dubiella, B. J. Pinch, D. Zaidman, T. D. Manz, E. Poon, S. He, E. Resnick, E. M. Langer, C. J. Daniel, H.-S. Seo, Y. Chen, S. B. Ficarro, Y. Jamin, X. Lian, S. Kibe, , N. London

Sulfopin, a selective Pin1 inhibitor, reduces tumor initiation and growth in neuroblastoma models by targeting c-Myc pathways.

bioRxiv · Mar 20, 2020 · PreprintCancer Biology

Fast transport of RNA granules by direct interactions with KIF5A/KLC1 motors prevents axon degeneration

R. A. Segal, H.-S. Seo, G. Adelmant, L. Walensky, J. A. Marto, S. Dhe-Paganon, Y. Fukuda, M. F. Pazyra-Murphy, O. E. Tasdemir-Yilmaz, Y. Li, L. Rose, Z. C. Yeoh, N. E. Vangos, E. A. Geffken, G. H. Bird

The paper identifies a mechanism by which RNA granules are transported via direct interaction with KIF5A/KLC1 motors, preventing axon degeneration in CMT models.

bioRxiv · Feb 2, 2020Cell Biology