Author

T. Mizutani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

T. Omatsu· 2 shared Y. Katayama· 2 shared A. R. Black· 1 shared C. Guda· 1 shared C. Rao· 1 shared D. E. Frodyma· 1 shared H. Arai· 1 shared H. Clever· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersEvolutionary Biology

T. Omatsu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Distinct Effects of the Male-Killing Bacteria Wolbachia and Spiroplasma and a Partiti-Like Virus in the Tea Pest Moth, Homona magnanima

H. Arai, T. Takamatsu, S. R. Lin, T. Mizutani, T. Omatsu, Y. Katayama, M. Nakai, Y. Kunimi, M. N. Inoue

This study compares the effects of three male-killing microbes in the tea pest moth, showing they use distinct mechanisms to kill male hosts.

bioRxiv · Apr 29, 2022Evolutionary Biology

Development of PRPK Directed Phthalimides

H.-S. Seo, T. Mizutani, T. Hideshima, N. E. Vangos, T. Zhang, K. C. Anderson, N. S. Gray, S. Dhe-Paganon

This paper develops PRPK-directed phthalimides based on pomalidomide, identifies a potent and selective PRPK binder, and highlights distinct binding mechanisms compared to cereblon.

bioRxiv · Nov 30, 2021 · PreprintBiochemistry

KSR1-and ERK-dependent Translational Regulation of the Epithelial-to-Mesenchymal Transition

C. Rao, D. E. Frodyma, S. Southekal, R. A. Svoboda, A. R. Black, C. Guda, T. Mizutani, H. Clever, K. R. Johnson, K. W. Fisher, R. E. Lewis

This study shows KSR1 and ERK promote EMT by selectively translating EPSTI1, which facilitates the E-to N-cadherin switch and enhances migration and invasion in CRC cells.

bioRxiv · Jan 18, 2021Cancer Biology

A novel defective recombinant porcine enterovirus G virus carrying a porcine torovirus papain-like cysteine protease gene and a putative anti-apoptosis gene in place of viral structural protein genes

R. Imai, M. Nagai, S. Sakaguchi, T. Masuda, M. Kuroda, M. Oba, Y. Katayama, Y. Naoi, S. Tsuchiaka, T. Omatsu, H. Yamazato, S. Makino, T. Mizutani

The paper identifies a novel recombinant porcine EV-G virus with a porcine torovirus PLCP gene replacing viral structural genes, and suggests a potential helper virus role for type 1 recombinant EV-G.

bioRxiv · Jan 2, 2019Microbiology