Author

N. KC

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Organism:mouse· 1

Frequent Co-Authors

S. Chakravarty· 3 shared S. L. Hoffman· 3 shared A. H. Idris· 2 shared B. K. L. Sim· 2 shared H. J. Sutton· 2 shared I. A. Cockburn· 2 shared K. E. Lyke· 2 shared R. A. Seder· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

S. Chakravarty

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Author profile →

3 papers

Recent·Most cited

Mapping of safe and early chemo-attenuated live Plasmodium falciparum immunization identifies immune signature of vaccine efficacy

S. Borrmann, Z. Sulyok, K. Mueller, R. Fendel, C. Lamsfus Calle, M. Sulyok, J. Friesen, A. Lalremruata, T. L. Sandri, T. T. Nguyen, A. Knoblich, S. Sefried, J. Ibanez, F.-R. Lorenz, H. L. Heimann, , B. Mordmueller

This study evaluates the safety and efficacy of chemo-attenuated Plasmodium falciparum immunization, identifying immune signatures that correlate with vaccine protection.

bioRxiv · Sep 14, 2020Immunology

Atypical B cells are a normal component of immune responses to vaccination and infection in humans

H. J. Sutton, R. Aye, A. H. Idris, R. Vistein, E. Nduati, O. Kai, J. Mwacharo, L. Xi, X. Gao, D. Andrews, M. Koutsakos, T. H. O. Nguyen, M. Nekrasov, P. Milburn, A. Ethala, , I. A. Cockburn

This study identifies atypical B cells as a normal part of immune responses to vaccination and infection in humans, showing they are present in both malaria-exposed and healthy individuals.

bioRxiv · May 28, 2020 · PreprintImmunology

Antibody feedback limits the expansion of cognate memory B cells but drives the diversification of vaccine-induced antibody responses

H. A. McNamara, A. H. Idris, H. J. Sutton, B. J. Flynn, Y. Cai, K. Wiehe, K. E. Lyke, D. Chatterjee, N. KC, S. Chakravarty, K. L. Sim, S. L. Hoffman, M. Bonsignori, R. A. Seder, I. A. Cockburn

The paper shows antibody feedback limits memory B cell expansion but allows diversification of vaccine-induced antibody responses by suppressing dominant epitopes while enabling subdominant ones.

bioRxiv · Oct 18, 2019 · PreprintImmunology