Author

S. Turville

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 8 Approach:experimental assay· 7 Organism:human· 5 Assay:proteomics· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Aggarwal· 5 shared A. Stella· 3 shared A. J. Cole· 2 shared A. Kelleher· 2 shared A. O. Stella· 2 shared C. Counoupas· 2 shared C. L. Moreno· 2 shared D. Hesselson· 2 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersImmunology

A. Aggarwal

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

P-Selectin promotes SARS-CoV-2 interactions with platelets and the endothelium

C. L. Moreno, F. V. S. Castanheira, A. O. Stella, F. Chung, A. Aggarwal, A. J. Cole, L. Loo, A. Dupuy, Y. Kong, L. Hagimola, J. Fenwick, P. Coleman, M. Wilson, M. Bui-Marinos, D. Hesselson, , G. G. Neely

This study identifies P-selectin as a novel SARS-CoV-2 spike receptor that promotes viral interactions with platelets and endothelium, facilitating viral localization in airway capillaries.

bioRxiv · Feb 13, 2023Immunology

Fibroblast-expressed LRRC15 suppresses SARS-CoV-2 infection and controls antiviral and antifibrotic transcriptional programs.

L. Loo, M. A. Waller, C. L. Moreno, A. J. Cole, A. O. Stella, O.-T. Pop, A.-K. Jochum, O. H. Ali, C. E. Denes, Z. Hamoudi, F. Chung, A. Aggarwal, J. K. K. Low, K. Patel, R. Siddique, , G. G. Neely

This study identifies LRRC15 as a host factor that suppresses SARS-CoV-2 infection and regulates antiviral and antifibrotic transcriptional programs in fibroblasts.

bioRxiv · Nov 9, 2021 · PreprintCell Biology

Neutralising antibodies against the SARS-CoV-2 Delta variant induced by Alhydroxyquim-II-adjuvanted trimeric spike antigens

C. Counoupas, P. Pino, A. Stella, C. Ashley, H. Lukeman, N. Bhattacharyya, T. Tada, S. Anchisi, C. Metayer, J. Martinis, A. Aggarwal, B. Dcosta, J. Kint, M. Wurm, N. Landau, , J. A. Triccas

This study shows that Alhydroxiquim-II-adjuvanted trimeric spike antigens induce high-titre, cross-variant neutralising antibodies against SARS-CoV-2 in animal models.

bioRxiv · Aug 18, 2021Microbiology

Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection

L. Li, Y. Honda-Okubo, Y. Huang, H. Jang, M. A. Carlock, J. Baldwin, S. Piplani, A. G. Bebin-Blackwell, D. Forgacs, K. Sakamoto, A. Stella, S. Turville, T. Chataway, A. Colella, J. Triccas, , N. Petrovsky

This study develops a recombinant SARS-CoV-2 spike protein vaccine, Covax-19, formulated with Advax-SM adjuvant, showing protection against COVID-19 in mice and ferrets.

bioRxiv · Jul 3, 2021Immunology

Ageing impairs the airway epithelium defence response to SARS-CoV-2

A. Capraro, S. L. Wong, A. Adhikari, K. M. Allan, H. R. Patel, L. Zhong, M. Raftery, A. Jaffe, M. Yeang, A. Aggarwal, L. Wu, E. Pandzic, R. M. Whan, S. Turville, O. Vittorio, , S. A. Waters

This study investigates age-related differences in the nasal epithelium's response to SARS-CoV-2, finding that older adults have impaired host defense and lower viral load due to reduced host machinery expression.

bioRxiv · Apr 5, 2021 · PreprintImmunology

Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies

R. Rouet, O. Mazigi, G. J. Walker, D. B. Langley, M. Sobti, P. Schofield, H. Lenthall, J. Jackson, S. Ubiparipovic, J. Y. Henry, A. Abayasingam, D. Burnett, A. Kelleher, R. Brink, R. A. Bull, , D. Christ

This paper explores antibody maturation strategies to enhance the neutralization of SARS-CoV-2 using SARS-CoV-1 antibodies, finding that some variants show potent neutralization with IC50 of 160 ng/ml.

bioRxiv · Dec 14, 2020Immunology

A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilizing immunity against SARS-CoV-2 infection in mice

C. Counoupas, M. D. Johnson, A. Stella, D. H. Nguyen, A. Ferguson, A. Aggarwal, N. Bhattacharyya, A. Grey, K. Patel, R. Siddiquee, E. L. Stewart, O. Hutchings, C. Feng, N. G. G. Hansbro, U. Palendira, , J. A. Triccas

A BCG-adjuvanted vaccine provides sterilizing immunity against SARS-CoV-2 in mice, with high neutralizing antibody titers and Th1 responses.

bioRxiv · Dec 10, 2020 · PreprintMicrobiology

Fluorescence biosensor for real-time interaction dynamics of host proteins with HIV-1 capsid tubes

D. Lau, J. Walsh, W. Peng, V. Shah, S. Turville, D. Jacques, T. Böcking

This paper develops a fluorescence biosensor to quantify host protein interactions with HIV-1 capsid tubes in real-time using total internal reflection fluorescence microscopy.

bioRxiv · May 17, 2019Biophysics