Author

N. S. Baliga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Evolutionary Biology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:human· 5 Approach:statistical model· 4 Research Focus:drug response / drug discovery· 3 Research Focus:host-pathogen & immune response· 3 Assay:metagenomics· 3 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

S. Turkarslan· 4 shared J. J. Valenzuela· 3 shared J. Wilson· 3 shared S. M. Gibbons· 3 shared C. Diener· 2 shared D. A. Stahl· 2 shared E. J. R. Peterson· 2 shared J. D. Mougous· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersMicrobiology

S. Turkarslan

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Origin of biogeographically distinct ecotypes during laboratory evolution

N. S. Baliga, J. J. Valenzuela, S. R. C. Immanuel, J. Wilson, S. Turkarslan, M. Ruiz, S. M. Gibbons, K. A. Hunt, M. Auer, M. Zemla, D. A. Stahl

This study shows how mutations in microbial species lead to resource partitioning and improved community productivity in a simulated subsurface environment.

bioRxiv · May 19, 2023Microbiology

Genetic manipulation of candidate phyla radiation bacteria provides functional insights into microbial dark matter

Y. Wang, L. A. Gallagher, P. A. Andrade, A. Liu, I. R. Humphreys, S. Turkarslan, K. J. Cutler, M. L. Arrieta-Ortiz, Y. Li, M. C. Radey, J. S. McLean, Q. Cong, D. Baker, N. S. Baliga, S. B. Peterson, J. D. Mougous

The paper genetically manipulates Saccharibacteria from the CPR to study their role in epibiotic growth and develops bioinformatic resources for their analysis.

bioRxiv · May 2, 2023Microbiology

Discovery of a unique pathway for glutathione utilization in Francisella

Y. Wang, H. E. Ledvina, C. A. Tower, S. Kambarev, E. Liu, J. C. Charity, L. S. M. Kreuk, Q. Chen, L. A. Gallagher, M. C. Radey, G. F. Rerolle, Y. Li, K. M. Penewit, S. Turkarslan, S. J. Skerrett, , J. D. Mougous

This study identifies a unique GSH utilization pathway in Francisella, revealing a pseudogenized transporter gene in pathogenic strains and its role in environmental niches.

bioRxiv · Feb 2, 2023Microbiology

Growth phase estimation for abundant bacterial populations sampled longitudinally from human stool metagenomes.

J. J. Lim, C. Diener, J. Wilson, J. J. Valenzuela, N. S. Baliga, S. M. Gibbons

This paper estimates growth phases of gut bacterial populations in human stool metagenomes using a steady-state flow-through model, finding slower defecation correlates with more taxa in later growth phases.

bioRxiv · Apr 23, 2022Ecology

Transcriptome signature of cell viability predicts drug response and drug interaction for Tuberculosis

V. Srinivas, R. A. Ruiz, M. Pan, S. R. C. Immanuel, E. J. R. Peterson, N. S. Baliga

This paper develops algorithms to predict drug response and interactions in tuberculosis by analyzing transcriptome signatures of cell viability.

bioRxiv · Feb 9, 2021 · PreprintMicrobiology

Autophagy as a mechanism for adaptive prediction-mediated emergence of drug resistance

N. Nivedita, J. D. Aitchison, N. S. Baliga

The paper shows that autophagy mutations linked to adaptive prediction confer drug tolerance and facilitate the emergence of drug resistance in yeast.

bioRxiv · Feb 2, 2021Evolutionary Biology

Synergistic epistasis enhances cooperativity of mutualistic interspecies interactions

S. Turkarslan, N. Stopnisek, A. W. Thompson, C. E. Arens, J. J. Valenzuela, J. Wilson, K. A. Hunt, J. Hardwicke, S. Lim, Y. M. Seah, Y. Fu, L. Wu, J. Zhou, K. L. Hillesland, D. A. Stahl, N. S. Baliga

The paper investigates how synergistic epistasis enhances cooperativity in mutualistic interspecies interactions between Desulfovibrio vulgaris and Methanococcus maripaludis under varying sulfate conditions.

bioRxiv · Jun 22, 2020Evolutionary Biology

PerSort facilitates characterization and elimination of persister subpopulation in mycobacteria

V. Srinivas, M. L. Arrieta-Ortiz, E. J. R. Peterson, N. S. Baliga

PerSort isolates and characterizes persister subpopulations in Mycobacterium tuberculosis, revealing their multidrug tolerance and metabolic state, and enabling their elimination under stress conditions.

bioRxiv · Apr 30, 2020Microbiology

Negative plant-microbiome feedback limits productivity in aquaponics

J. A. Day, A. E. Otwell, C. Diener, K. E. Tams, B. M. Bebout, A. M. Detweiler, M. D. Lee, M. T. Scott, W. Ta, M. Ha, S. A. Carreon, K. Tong, A. A. Ali, S. M. Gibbons, N. S. Baliga

This study shows that transferring established microbiomes to aquaponic systems reduces lettuce growth due to pathogen enrichment, highlighting negative feedback mechanisms similar to soil ecology.

bioRxiv · Aug 28, 2019 · PreprintMicrobiology