Author

L. A. Gallagher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. D. Mougous· 4 shared S. B. Peterson· 4 shared M. C. Radey· 3 shared Y. Li· 3 shared Y. Wang· 3 shared H. E. Ledvina· 2 shared K. J. Cutler· 2 shared K. M. Penewit· 2 shared

Activity by Year

2021-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersMicrobiology

J. D. Mougous

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Umbrella toxin particles produced by Streptomyces block mycelial growth of competing species

Q. Zhao, S. Bertolli, Y.-J. Park, Y. Tan, K. J. Cutler, P. Srinivas, K. L. Asfahl, C. Fonseca Garcia, L. A. Gallagher, Y. Li, Y. Wang, D. Coleman-Derr, F. DiMaio, D. Zhang, S. B. Peterson, , J. D. Mougous

This study identifies umbrella toxin particles produced by Streptomyces that inhibit the growth of competing bacterial species, distinct from small molecule antibiotics.

bioRxiv · Dec 9, 2023 · PreprintMicrobiology

Genetic manipulation of candidate phyla radiation bacteria provides functional insights into microbial dark matter

Y. Wang, L. A. Gallagher, P. A. Andrade, A. Liu, I. R. Humphreys, S. Turkarslan, K. J. Cutler, M. L. Arrieta-Ortiz, Y. Li, M. C. Radey, J. S. McLean, Q. Cong, D. Baker, N. S. Baliga, S. B. Peterson, J. D. Mougous

The paper genetically manipulates Saccharibacteria from the CPR to study their role in epibiotic growth and develops bioinformatic resources for their analysis.

bioRxiv · May 2, 2023Microbiology

Metabolic reprogramming and flux to cell envelope precursors in a pentose phosphate pathway mutant increases MRSA resistance to β-lactam antibiotics

M. S. Zeden, L. A. Gallagher, E. Bueno, A. Nolan, J. Ahm, D. Shinde, F. Razvi, M. Sladek, O. Burke, E. O'Neill, P. D. Fey, F. Cava, V. C. Thomas, J. P. O'Gara

This study shows that mutating the pentose phosphate pathway gene pgl in MRSA increases resistance to beta-lactam antibiotics through metabolic reprogramming and changes in cell envelope precursors.

bioRxiv · Mar 3, 2023 · PreprintMicrobiology

Discovery of a unique pathway for glutathione utilization in Francisella

Y. Wang, H. E. Ledvina, C. A. Tower, S. Kambarev, E. Liu, J. C. Charity, L. S. M. Kreuk, Q. Chen, L. A. Gallagher, M. C. Radey, G. F. Rerolle, Y. Li, K. M. Penewit, S. Turkarslan, S. J. Skerrett, , J. D. Mougous

This study identifies a unique GSH utilization pathway in Francisella, revealing a pseudogenized transporter gene in pathogenic strains and its role in environmental niches.

bioRxiv · Feb 2, 2023Microbiology

Coordinately regulated interbacterial antagonism defense pathways constitute a bacterial innate immune system

S.-Y. Ting, K. D. LaCourse, H. E. Ledvina, R. Zhang, M. C. Radey, H. D. Kulasekara, R. Somavanshi, S. K. Bertolli, L. A. Gallagher, J. Kim, K. M. Penewit, S. J. Salipante, L. Xu, S. B. Peterson, J. D. Mougous

This study identifies three conserved interbacterial antagonism resistance clusters in Pseudomonas aeruginosa that function independently and provide specific defense against phospholipase toxins.

bioRxiv · Aug 22, 2021Microbiology