Author

Natalie Pushlar

Sanford Burnham Prebys Medical Discovery Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron ShulkiniD· 1 shared Abigail Sondrini· 1 shared Alberto BosqueiD· 1 shared Alicja K. TrochaiD· 1 shared Alper KüçükuraliD· 1 shared Amanda Modica· 1 shared Emily Smith· 1 shared Evan Y. Snyder· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Aaron ShulkinORCID

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Author profile →

2 papers

Recent·Most cited

Loss of Vpr-driven TRAIL-R2 expression protects HIV-infected cells from non-canonical NK cell TRAIL attack

Paula E. Grasberger, Abigail Sondrini, Nicole C. Glidden, Amanda Modica, Natalie Pushlar, Seden Bedir, Tara Bromfield, Sheldon Gentling, Komal Cheema, Alper Küçükural, Milena Ozdemir, Maria L. Zapp, Alberto Bosque, Louise Leyre, Aaron Shulkin, , Kiera Clayton

The paper shows HIV uses Vpr to increase TRAIL-R2 expression in CD4+ T cells, which enhances NK cell killing through non-canonical TRAIL signaling.

bioRxiv · Apr 19, 2026 · PreprintImmunology

Modeling the Aging Human Lung: Generation of a Senescent Human Lung Organoid Culture System

Mohit Aspal, Natalie Pushlar, Melina Melameka, Rachael N. McVicar, Emily Smith, Temiloluwa Ogunyamoju, Matangi Kumar, Jamey D. Marth, Jerold J. M. Chun, Evan Y. Snyder, Sandra Lawrynowicz Leibel

This paper develops a human lung organoid model to study senescence, showing increased β-gal activity, SASP cytokines, and fibrosis-like features.

bioRxiv · Feb 24, 2025 · PreprintCell Biology