Author

O. J. Luo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

G. Chen· 3 shared G. Zhu· 3 shared L. Gao· 3 shared C. Xiao· 2 shared F. Gao· 2 shared H. Niu· 2 shared J. Su· 2 shared L. Mao· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

G. Chen

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3 papers

Recent·Most cited

SARS-CoV-2 variant B.1.1.7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response

C. Xiao, L. Mao, Z. Wang, G. Zhu, L. Gao, J. Su, X. Chen, J. Yuan, Y. Hu, Z. Yin, J. Xie, W. Ji, H. Niu, F. Gao, O. J. Luo, , G. Chen

This study identifies mutations in SARS-CoV-2 variant B.1.1.7 that reduce HLA-A2 restricted CD8+ T cell epitope binding and impair cellular immune responses.

iScience · Mar 1, 2022Peer-reviewedImmunology

Identification of age and ethnicity specific gene expression biomarkers for immune aging

Y. Hu, Y. Xu, L. Mao, J. Xiang, W. Lei, G. Zhu, Y. Hu, H. Niu, F. Gao, L. Gao, L. Huang, O. J. Luo, G. Chen

This study identifies age and ethnicity-specific gene expression biomarkers for immune aging using transcriptomic data from peripheral blood mononuclear cells.

bioRxiv · Feb 22, 2021 · PreprintImmunology

CD8+ T cell epitope variations suggest a potential antigen presentation deficiency for spike protein of SARS-CoV-2

C. Qiu, C. Xiao, Z. Wang, G. Zhu, X. Chen, L. Gao, J. Den, J. Su, H. Su, E. F. Fang, Z. Zhang, J. Zhang, O. J. Luo, P. Wang, G. Chen

The paper identifies HLA-A2 restricted T cell epitopes in SARS-CoV-2 spike protein and finds that variations in these epitopes may reduce T cell activation and contribute to immune escape.

bioRxiv · Jan 22, 2021 · PreprintImmunology