Author

K. L. Miners

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

D. A. Price· 3 shared K. Ladell· 3 shared D. M. Chudakov· 2 shared O. V. Britanova· 2 shared V. V. Kriukova· 2 shared A. Cardus-Figueras· 1 shared A. Franke· 1 shared A. J. Davison· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

D. A. Price

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Repertoire-based mapping and time-tracking of helper T cell subsets in scRNA-Seq

D. K. Lukyanov, V. V. Kriukova, K. Ladell, I. A. Shagina, D. B. Staroverov, B. Minasian, A. S. Fedosova, P. Shelyakin, O. N. Suchalko, A. Komkov, K. A. Blagodatskikh, K. L. Miners, O. V. Britanova, A. Franke, D. A. Price, D. M. Chudakov

This paper introduces TCR-Track, a method to map and track helper T cell subsets in scRNA-Seq data, revealing their clonal relationships and functional programs over time.

bioRxiv · Oct 24, 2023Immunology

ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways

A. Rubina, M. Patel, K. Nightingale, M. Potts, C. A. Fielding, S. Kollnberger, B. Lau, K. Ladell, K. L. Miners, J. Nichols, L. Nobre, D. Roberts, T. M. Trinca, J. P. Twohig, V.-M. Vlahava, , E. C. Y. Wang

This paper identifies how HCMV targets ADAM17 to modulate surface proteins and immune pathways, revealing a novel viral immunomodulation strategy.

bioRxiv · Mar 16, 2023Microbiology

Inhibitory IL-10-producing CD4+ T cells develop in a T-bet-dependent manner and facilitate cytomegalovirus persistence via coexpression of arginase-1

M. Clement, K. Ladell, K. L. Miners, M. Marsden, L. Chapman, A. Cardus-Figueras, J. Scott, R. Andrews, S. Clare, V. V. Kriukova, K. R. Lupyr, O. V. Britanova, D. R. Withers, D. M. Chudakov, S. A. Jones, , I. Humphreys

The paper identifies IL-10-producing CD4+ T cells that develop via T-bet dependence and Arg1 coexpression, promoting cytomegalovirus persistence.

bioRxiv · Jan 25, 2022Immunology