Author

L. Chapman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Clement· 2 shared M. Marsden· 2 shared A. Cardus-Figueras· 1 shared A. Reginald· 1 shared C. Salguero Aranda· 1 shared D. A. Price· 1 shared D. M. Chudakov· 1 shared D. R. Withers· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

M. Clement

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inhibitory IL-10-producing CD4+ T cells develop in a T-bet-dependent manner and facilitate cytomegalovirus persistence via coexpression of arginase-1

M. Clement, K. Ladell, K. L. Miners, M. Marsden, L. Chapman, A. Cardus-Figueras, J. Scott, R. Andrews, S. Clare, V. V. Kriukova, K. R. Lupyr, O. V. Britanova, D. R. Withers, D. M. Chudakov, S. A. Jones, , I. Humphreys

The paper identifies IL-10-producing CD4+ T cells that develop via T-bet dependence and Arg1 coexpression, promoting cytomegalovirus persistence.

bioRxiv · Jan 25, 2022Immunology

Optimal CD8+ T-cell memory formation following subcutaneous cytomegalovirus infection requires virus replication but not early dendritic cell responses

S. Dimonte, S. Gimeno-Brias, M. Marsden, L. Chapman, P. Sabberwal, M. Clement, I. R. Humphreys

bioRxiv · Dec 2, 2020Immunology

STAT6 mRNA and protein knockdown using multiple siRNA sequences inhibits proliferation and induces apoptosis of the human colon adenocarcinoma cell line, HT-29

C. Salguero Aranda, D. Sancho Mensat, S. Sultan, A. Reginald, L. Chapman

The paper tests four STAT6-specific siRNA sequences in HT-29 colon cancer cells, showing they reduce STAT6 expression and inhibit proliferation while inducing apoptosis.

bioRxiv · Nov 5, 2018Cancer Biology