Author

P. Brzovic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. B. Russell· 1 shared A. L. Sapiro· 1 shared A. Radkov· 1 shared A. Zelter· 1 shared B. Hayes· 1 shared C. Henderson· 1 shared C. Mateusiak· 1 shared D. B. Wilburn· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperBiochemistry

A. B. Russell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation.

S. R. Witus, L. M. Tuttle, W. Li, A. Zelter, M. Wang, K. E. Kermoade, D. B. Wilburn, T. N. Davis, P. Brzovic, W. Zhao, R. E. Klevit

This study identifies intrinsically disordered regions in BRCA1/BARD1 that mediate chromatin recruitment and ubiquitylation, enhancing DNA damage repair and transcriptional regulation.

bioRxiv · Aug 9, 2022Biochemistry

Antibacterial potency of Type VI amidase effector toxins is dependent on substrate topology and cellular context

A. Radkov, A. L. Sapiro, S. Flores, C. Henderson, H. Saunders, R. Kim, S. Massa, S. Thompson, C. Mateusiak, J. Biboy, Z. Zhao, L. M. Starita, W. Hatleberg, W. Vollmer, A. B. Russell, , S. Chou

This study identifies functional determinants of Tae1, a bacterial T6SS amidase toxin, showing that its antimicrobial potency depends on substrate topology and cellular context.

bioRxiv · Feb 15, 2022Biochemistry

The Evolution of SlyA/RovA Transcription Factors From Repressors to Counter-Silencers in Enterobacteriaceae

W. R. Will, P. Brzovic, I. Le Trong, R. E. Stenkamp, M. B. Lawrenz, J. E. Karlinsey, W. W. Navarre, K. Main-Hester, V. L. Miller, S. J. Libby, F. C. Fang

The paper examines the evolution of SlyA/RovA transcription factors in Enterobacteriaceae, showing their transition from repressors to counter-silencers that facilitate horizontal gene transfer.

bioRxiv · Dec 11, 2018Microbiology