Author

L. Carrau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Organism:Arabidopsis· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

B. R. tenOever· 2 shared M. Vignuzzi· 2 shared A. Hardy· 1 shared A. Henrion Lacritick· 1 shared A. J. Samelson· 1 shared A. M. Brown· 1 shared A. Mac Kain· 1 shared B. C. Lubor· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

B. R. tenOever

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito

F. Roesch, C. Cereghino, L. Carrau, A. Hardy, H. Ribeiro-Filho, A. Henrion Lacritick, C. Koh, J. Marano, T. A. Bates, P. Rai, C. Chuong, S. Akter, T. Vallet, H. Blanc, T. Elliot, , J. Weger-Lucarelli

This paper identifies a mutation in the E2 glycoprotein of Mayaro virus that enhances transmission in Aedes aegypti but reduces replication in human cells, suggesting a trade-off in host adaptation.

bioRxiv · Apr 5, 2022 · PreprintMicrobiology

SARS-CoV-2 Infects Syncytiotrophoblast and Activates Inflammatory Responses in the Placenta

L. B. Argueta, L. A. Lacko, Y. Bram, T. Tada, L. Carrau, T. Zhang, S. Uhl, B. C. Lubor, V. Chandar, C. Gil, W. Zhang, B. Dodson, J. Bastiaans, M. Prabhu, C. M. Salvatore, , H. Stuhlmann

This study investigates SARS-CoV-2 infection in placentas from infected pregnant women, finding that the virus infects syncytiotrophoblast cells and triggers maternal immune cell infiltration.

bioRxiv · Jun 1, 2021Cell Biology

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

A. J. Samelson, Q. D. Tran, R. Robinot, L. Carrau, V. V. Rezelj, A. Mac Kain, M. Chen, G. N. Ramadoss, X. Guo, S. A. Lim, I. Lui, J. Nunez, S. J. Rockwood, J. Wang, N. Liu, , M. Kampmann

This study identifies BRD2 as a regulator of ACE2 transcription and shows that BRD2 inhibitors block SARS-CoV-2 infection in human cells and animal models.

bioRxiv · Jan 19, 2021Cell Biology