Author

P. O. Scumpia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:development & morphogenesis· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

J. S. Weinstein· 3 shared D. Di Carlo· 2 shared D. P. Mayer· 2 shared K. M. Kelly-Scumpia· 2 shared M. M. Archang· 2 shared O. Q. Antao· 2 shared A. C. Feng· 1 shared A. Ruccia· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersBioengineering

J. S. Weinstein

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A novel microporous biomaterial vaccine platform for long-lasting antibody mediated immunity against viral infection.

D. P. Mayer, M. Nelson, D. Andriyanova, O. Q. Antao, J. S. Chen, P. O. Scumpia, W. M. Weaver, S. Deshayes, J. S. Weinstein

This paper develops a novel microporous biomaterial vaccine platform, VaxMAP, which enhances antibody-mediated immunity against viral infections compared to traditional vaccines.

bioRxiv · Jan 30, 2024Immunology

Improved humoral immunity and protection against influenza virus infection with a 3D porous biomaterial vaccine

H. Miwa, O. Q. Antao, K. M. Kelly-Scumpia, S. Baghdasarian, D. P. Mayer, L. Shang, G. M. Sanchez, M. M. Archang, P. O. Scumpia, J. S. Weinstein, D. Di Carlo

This paper develops a 3D porous biomaterial vaccine platform that enhances humoral immunity and protection against influenza virus by tuning physical and chemical properties.

bioRxiv · Dec 16, 2022Bioengineering

Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing.

D. R. Griffin, M. M. Archang, C. H. Kuan, W. Weaver, J. S. Weinstein, A. C. Feng, A. Ruccia, E. Sideris, V. Ragkousis, J. Koh, M. V. Plikus, D. Di Carlo, T. Segura, P. O. Scumpia

This study shows that D-peptide crosslinked hydrogels induce adaptive immune responses that promote regenerative wound healing despite faster degradation.

bioRxiv · May 27, 2020Bioengineering

A Macrophage Response To Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage In Leprosy

C. A. Madigan, C. Cambier, K. M. Kelly-Scumpia, P. O. Scumpia, T.-Y. Cheng, J. Zailaa, B. R. Bloom, D. B. Moody, S. T. Smale, A. Sagasti, R. L. Modlin, L. Ramakrishnan

The paper shows that M. leprae's PGL-1 toxin triggers macrophages to damage nerves by inducing nitric oxide, leading to axon demyelination in leprosy.

bioRxiv · Apr 17, 2017Microbiology