Author

P. Patil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. M. Hasty· 2 shared B. R. Dollinger· 2 shared C. L. Duvall· 2 shared F. Yu· 2 shared S. S. Patel· 2 shared A. Barbul· 1 shared A. C. Pollins· 1 shared A. Cavnar· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

A. M. Hasty

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural Optimization of siRNA Conjugates for Albumin Binding Achieves Effective MCL1-Targeted Cancer Therapy

E. Hoogenboezem, S. S. Patel, A. Cavnar, J. Lo, L. Babb, N. Francini, P. Patil, J. Colazo, D. L. Michell, V. Sanchez, J. McCune, J. Ma, C. DeJulius, L. Lee, J. Rosch, , C. Duvall

This paper optimizes siRNA conjugates for albumin binding to enhance tumor delivery and efficacy in cancer therapy, achieving 80% MCL1 silencing and improved survival in breast cancer models.

bioRxiv · Feb 14, 2023 · PreprintBioengineering

ROS-Degradable Polythioketal Urethane Foam Dressings to Promote Porcine Skin Wound Repair

P. Patil, K. A. Russo, J. T. McCune, A. C. Pollins, M. A. Cottom, B. R. Dollinger, J. M. Colazo, F. Yu, J. R. Martin, M. K. Gupta, N. L. Cardwell, J. M. Davidson, C. M. Thompson, A. Barbul, A. M. Hasty, , C. L. Duvall

This paper develops ROS-degradable polythioketal urethane foams for skin wound healing, showing improved tissue integration and ECM deposition compared to existing materials.

bioRxiv · May 21, 2021 · PreprintBioengineering

Kupffer Cell Release of Platelet Activating Factor Drives Dose Limiting Toxicities of Nucleic Acid Nanocarriers

M. A. Jackson, S. S. Patel, F. Yu, M. A. Cottam, E. B. Glass, B. R. Dollinger, E. N. Hoogenboezem, P. Patil, D. D. Liu, I. B. Kelly, S. K. Bedingfield, A. R. King, R. E. Miles, A. M. Hasty, T. D. Giorgio, C. L. Duvall

This paper identifies Kupffer cell release of platelet activating factor (PAF) as a key driver of nanocarrier toxicity and shows that PAFR inhibition prevents dose-limiting toxicities in mice.

bioRxiv · Feb 11, 2020Bioengineering

A strain of an emerging Indian pathotype of Xanthomonas oryzae pv. oryzae defeats the rice bacterial blight resistance gene xa13 without inducing a clade III SWEET gene and is nearly identical to a recent Thai isolate

S. Carpenter, P. Mishra, C. Ghoshal, P. Dash, L. Wang, S. Midha, G. S. Laha, J. Lore, W. Kositratana, N. Singh, K. Singh, P. Patil, R. Oliva, S. Patarapuwadol, A. J. Bogdanove, R. Rai

The paper identifies an Xoo strain that bypasses xa13 resistance by not inducing clade III SWEET genes and is nearly identical to a Thai isolate.

bioRxiv · Aug 6, 2018Pathology