Author

Paul Sylvester

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam M. DrobishiD· 1 shared Amanda J. GrammiD· 1 shared Bose Muthu Ramalingam· 1 shared Che-Kang ChangiD· 1 shared Craig E. CameroniD· 1 shared Daniel N. StreblowiD· 1 shared Durbadal OjhaiD· 1 shared Ganesh S. AnandiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Adam M. DrobishORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Identification of a Broadly Acting Inhibitor of the Alphavirus Non-Structural Protein 2 Helicase

John D. Sears, Durbadal Ojha, Sharon Taft-Benz, Paul Sylvester, Zachary J. Streblow, Amanda J. Gramm, Adam M. Drobish, Bose Muthu Ramalingam, Mohammad Anwar Hossain, Kacey Marie Talbot, Wes Sanders, Che-Kang Chang, Isabella Law, Sabian A. Martinez, Jane Burdick, , Nathaniel J. Moorman

This study identifies a first-in-class inhibitor of alphavirus nsP2 helicase activity, showing broad antiviral activity and in vivo efficacy against chikungunya virus.

bioRxiv · Jun 3, 2025 · PreprintMicrobiology