R. Chauhan

CDK4/6 inhibition and dsRNA sensor agonism co-operate to enhance anti-cancer effects through ER stress and immune modulation of tumour cells

Insights into the role of Nup62 and Nup93 in assembling cytoplasmic ring and central transport channel of the nuclear pore complex

This study investigates the role of Nup62 and Nup93 in NPC assembly, revealing their interactions and structural contributions to the cytoplasmic ring and central transport channel.

Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates

This paper evaluates an AAV-based COVID-19 vaccine in mice and non-human primates, showing sustained neutralizing antibodies and memory T-cells, with room-temperature stability and scalable production.

Negative selection may cause grossly altered but broadly stable karyotypes in metastatic colorectal cancer

This study analyzes longitudinal genomic data from colorectal cancer patients to show that negative selection stabilizes karyotypes during tumor progression and metastasis.

Evolutionary divergence of novel open reading frames in cichlids speciation

This study identifies and analyzes novel open reading frames (nORFs) in two cichlid species, suggesting their potential role in speciation and evolutionary divergence.