Author

R. Gopalappa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. Georgakopoulos· 1 shared D. H. Jo· 1 shared D. Seo· 1 shared G. Yu· 1 shared H. B. Kim· 1 shared H. H. Kim· 1 shared H. J. Lee· 1 shared H. Jang· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Georgakopoulos

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Author profile →

2 papers

Recent·Most cited

Prime editing enables precise genome editing in mouse liver and retina

H. Jang, J. H. Shin, D. H. Jo, J. H. Seo, G. Yu, R. Gopalappa, S.-R. Cho, J. H. Kim, H. H. Kim

This study demonstrates that prime editing can correct disease-causing mutations in adult mouse liver and retina, with minimal off-target effects.

bioRxiv · Jan 8, 2021 · PreprintBioengineering

Size-dependent protein segregation creates a spatial switch for Notch signaling and function

M. Kwak, K. M. Southard, N. H. Kim, R. Gopalappa, W. R. Kim, M. An, H. J. Lee, M. K. Kang, S. H. Choi, J. Farlow, A. Georgakopoulos, N. K. Robakis, D. Seo, H. B. Kim, Y. H. Kim, , Y.-w. Jun

The paper shows that spatial constraints at cadherin-based adherens junctions regulate Notch cleavage by gamma-secretase, affecting signaling and cell differentiation.

bioRxiv · Jun 28, 2020Cell Biology